Active matter at the interface between materials science and cell biology
D Needleman, Z Dogic - Nature reviews materials, 2017 - nature.com
The remarkable processes that characterize living organisms, such as motility, self-healing
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …
E-cadherin junctions as active mechanical integrators in tissue dynamics
During epithelial morphogenesis, E-cadherin adhesive junctions play an important part in
mechanically coupling the contractile cortices of cells together, thereby distributing the …
mechanically coupling the contractile cortices of cells together, thereby distributing the …
Actin cortex architecture regulates cell surface tension
Animal cell shape is largely determined by the cortex, a thin actin network underlying the
plasma membrane in which myosin-driven stresses generate contractile tension. Tension …
plasma membrane in which myosin-driven stresses generate contractile tension. Tension …
Modeling semiflexible polymer networks
CP Broedersz, FC MacKintosh - Reviews of Modern Physics, 2014 - APS
This is an overview of theoretical approaches to semiflexible polymers and their networks.
Such semiflexible polymers have large bending rigidities that can compete with the entropic …
Such semiflexible polymers have large bending rigidities that can compete with the entropic …
Mechanical properties of the cytoskeleton and cells
AF Pegoraro, P Janmey… - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
The cytoskeleton is the major mechanical structure of the cell; it is a complex, dynamic
biopolymer network comprising microtubules, actin, and intermediate filaments. Both the …
biopolymer network comprising microtubules, actin, and intermediate filaments. Both the …
Actin cortex mechanics and cellular morphogenesis
The cortex is a thin, crosslinked actin network lying immediately beneath the plasma
membrane of animal cells. Myosin motors exert contractile forces in the meshwork. Because …
membrane of animal cells. Myosin motors exert contractile forces in the meshwork. Because …
Apical constriction: themes and variations on a cellular mechanism driving morphogenesis
AC Martin, B Goldstein - Development, 2014 - journals.biologists.com
Apical constriction is a cell shape change that promotes tissue remodeling in a variety of
homeostatic and developmental contexts, including gastrulation in many organisms and …
homeostatic and developmental contexts, including gastrulation in many organisms and …
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex
MP Murrell, ML Gardel - Proceedings of the National …, 2012 - National Acad Sciences
Here we develop a minimal model of the cell actomyosin cortex by forming a quasi-2D cross-
linked filamentous actin (F-actin) network adhered to a model cell membrane and contracted …
linked filamentous actin (F-actin) network adhered to a model cell membrane and contracted …
Physics of adherent cells
US Schwarz, SA Safran - Reviews of Modern Physics, 2013 - APS
One of the most unique physical features of cell adhesion to external surfaces is the active
generation of mechanical force at the cell-material interface. This includes pulling forces …
generation of mechanical force at the cell-material interface. This includes pulling forces …
The actin cytoskeleton as an active adaptive material
S Banerjee, ML Gardel… - Annual review of …, 2020 - annualreviews.org
Actin is the main protein used by biological cells to adapt their structure and mechanics to
their needs. Cellular adaptation is made possible by molecular processes that strongly …
their needs. Cellular adaptation is made possible by molecular processes that strongly …