Background It is a daunting task to identify all the metabolic pathways of brain energy
metabolism and develop a dynamic simulation environment that will cover a time scale …

Advances in the field of genomics have enabled computational analysis of metabolic
pathways at the genome scale. Singular attention has been devoted in the literature to …

We present a generalised framework for analysing structural robustness of metabolic
networks, based on the concept of elementary flux modes (EFMs). Extending our earlier …

Motivation: In recent years, several methods have been proposed for determining metabolic
pathways in an automated way based on network topology. The aim of this work is to …

We study the structural robustness of metabolic networks on the basis of the concept of
elementary flux modes. It is shown that the number of elementary modes itself is not an …

Halomonas smyrnensis AADT is a halophilic, gram‐negative bacterium that can efficiently
produce levan from sucrose as carbon source via levansucrase activity. However, systems …

Metabolic control analysis (MCA) is a promising approach in biochemistry aimed at
understanding processes in a quantitative fashion. Here the contribution of enzymes and …

This paper describes the process for the reconstruction of a high quality human metabolic
network from the genome information, the existing problems in the reconstruction and why a …

This article is devoted to the study of redundancy and yield of salvage pathways in human
erythrocytes. These cells are not able to synthesize ATP de novo. However, the salvage …

Hyperbilirubinemia is prevalent in newborns and multiple factors are responsible for the
occurrence of neonatal hyperbilirubinemia. G6PD (Glucose-6-Phosphate Dehydrogenase) …