Background Thiopurine‐induced leukopenia, a frequently observed and potentially life‐
threatening adverse event, complicates the clinical management of IBD patients. Aim To …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gut
characterised by alternating periods of remission and relapse. Whilst the mechanism …

Thiopurines have been widely used for the maintenance of remission or steroid sparing in
patients with inflammatory bowel disease. However, potential drug-related adverse events …

Background There are safety concerns regarding immunomodulators (thiopurines and
methotrexate) for treatment of inflammatory bowel disease (IBD). Aim To compare the long …

Abstract Azathioprine (AZA) 2 to 2.5 mg/kg/d is recommended for European patients with
Crohn disease (CD), but several Asian studies reported that low dose of AZA was also …

Background Recent population-based study of elderly-onset Crohn's disease patients
reported age-related differences in disease phenotype and outcome. Aims The aim was to …

Introduction: Les thiopurines ont prouvé leur efficacité au cours des maladies inflammatoires
chroniques de l'intestin. Cependant, leur utilisation est limitée chez un sous-groupe de …

Pediatric dermatoses constitute an array of varied diseases, a few of which may require long-
term treatment with immunosuppressants in the form of corticosteroids (CS) and steroid …

Background Thiopurines are effective therapies for inflammatory bowel disease (IBD);
however, treatment comes with safety concerns and adverse effects. Knowledge of the …

Laboratory tests play an important role in clinical diagnosis, and the results often direct
patient management. Tests should be requested appropriately in order to refine the …