Pestiviruses are among the economically most important pathogens of livestock. The biology
of these viruses is characterized by unique and interesting features that are both crucial for …

Type I interferons (IFNs) play a crucial role in the innate immune avant-garde against viral
infections. Virtually all viruses have developed means to counteract the induction, signaling …

Classical swine fever (CSF) is among the most relevant viral epizootic diseases of swine.
Due to its severe economic impact, CSF is notifiable to the world organisation for animal …

Classical swine fever (CSF) represents a major health and trade problem for the pig
industry. In endemic countries or those with a wild boar reservoir, CSF remains a priority for …

Bovine viral diarrhea virus (BVDV), a Flaviviridae pestivirus, is arguably one of the most
widespread cattle pathogens worldwide. Each of its two genotypes has two biotypes, non …

The immune surveillance system protects host cells from viral infection, and viruses have
evolved to escape this system for efficient proliferation in the host. Host cells produce …

Classical swine fever (CSF) is a highly contagious and often fatal disease that affects
domestic pigs and wild boars. Outbreak of CSF can cause heavy economic losses to the pig …

Highlights•Coronaviruses employ versatile mechanisms to evade sensing of viral RNA.•Cap-
methylation of viral RNA facilitates innate immune evasion.•There is increasing evidence …

Animals persistently infected (PI) with bovine viral diarrhea virus (BVDV) retain a strain-
specific B-and T-cell immunotolerance. Pestiviral RNA triggers interferon (IFN) synthesis …

African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs
causing significant economic consequences to the swine industry. The ASFV genome …