Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

HB El–Serag, KL Rudolph - Gastroenterology, 2007 - Elsevier
Primary liver cancer, which consists predominantly of hepatocellular carcinoma (HCC), is
the fifth most common cancer worldwide and the third most common cause of cancer …

Gene map of the extended human MHC

R Horton, L Wilming, V Rand, RC Lovering… - Nature Reviews …, 2004 - nature.com
The major histocompatibility complex (MHC) is the most important region in the vertebrate
genome with respect to infection and autoimmunity, and is crucial in adaptive and innate …

Molecular mechanisms of hepatocellular carcinoma

RN Aravalli, CJ Steer, ENK Cressman - Hepatology, 2008 - journals.lww.com
Hepatocellular carcinoma (HCC) typically has poor prognosis, because it is often diagnosed
at an advanced stage. Heterogeneous phenotypic and genetic traits of affected individuals …

EASL clinical practice guidelines for HFE hemochromatosis

European Association For The Study Of The Liver - Journal of hepatology, 2010 - Elsevier
Iron overload in humans is associated with a variety of genetic and acquired conditions. Of
these, HFE hemochromatosis (HFE-HC) is by far the most frequent and most well-defined …

Hepatocellular carcinoma–epidemiological trends and risk factors

K Schütte, J Bornschein, P Malfertheiner - Digestive diseases, 2009 - karger.com
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths
worldwide with about 600,000 patients dying from the disease annually. In 70–90%, HCC …

Iron, hemochromatosis, and hepatocellular carcinoma

KV Kowdley - Gastroenterology, 2004 - Elsevier
Hereditary hemochromatosis (HH) is associated with an increased risk for hepatocellular
carcinoma (HCC). The risk previously had been estimated to be as high as 200-fold …

[HTML][HTML] Hepatitis C virus-induced hepatocellular carcinoma

N Goossens, Y Hoshida - Clinical and molecular hepatology, 2015 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a leading etiology of hepatocellular carcinoma (HCC). The
interaction of HCV with its human host is complex and multilayered; stemming in part from …

Reclassifying hepatic cell death during liver damage: ferroptosis—a novel form of non-apoptotic cell death?

RU Macías-Rodríguez, ME Inzaugarat… - International journal of …, 2020 - mdpi.com
Ferroptosis has emerged as a new type of cell death in different pathological conditions,
including neurological and kidney diseases and, especially, in different types of cancer. The …

[HTML][HTML] Non-viral causes of hepatocellular carcinoma

W Blonski, DS Kotlyar, KA Forde - World journal of …, 2010 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and
represents an international public health concern as one of the most deadly cancers …

Epidemiology of primary and secondary liver cancers

A Ananthakrishnan, V Gogineni… - Seminars in …, 2006 - thieme-connect.com
Primary liver cancer is the sixth most common cancer worldwide with a wide geographic
distribution. The incidence of primary liver cancer is increasing and there is still a higher …