Differences between human and chimpanzee genomes and their implications in gene expression, protein functions and biochemical properties of the two species

MV Suntsova, AA Buzdin - BMC genomics, 2020 - Springer
Chimpanzees are the closest living relatives of humans. The divergence between human
and chimpanzee ancestors dates to approximately 6, 5–7, 5 million years ago. Genetic …

Molecular functions of human endogenous retroviruses in health and disease

M Suntsova, A Garazha, A Ivanova, D Kaminsky… - Cellular and Molecular …, 2015 - Springer
Human endogenous retroviruses (HERVs) and related genetic elements form 504 distinct
families and occupy~ 8% of human genome. Recent success of high-throughput …

[图书][B] Human evolutionary genetics: origins, peoples and disease

M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

Viruses are essential agents within the roots and stem of the tree of life

LP Villarreal, G Witzany - Journal of Theoretical Biology, 2010 - Elsevier
In contrast with former definitions of life limited to membrane-bound cellular life forms which
feed, grow, metabolise and replicate (i) a role of viruses as genetic symbionts,(ii) along with …

Impact of transposable elements on the evolution of mammalian gene regulation

P Medstrand, LN van de Lagemaat, CA Dunn… - … and genome research, 2005 - karger.com
Transposable elements (TEs) are present in all organisms and nearly half of the human and
mouse genome is derived from ancient transpositions. This fact alone suggests that TEs …

At least 50% of human-specific HERV-K (HML-2) long terminal repeats serve in vivo as active promoters for host nonrepetitive DNA transcription

A Buzdin, E Kovalskaya-Alexandrova… - Journal of …, 2006 - Am Soc Microbiol
We report the first genome-wide comparison of in vivo promoter activities of a group of
human-specific endogenous retroviruses in healthy and cancerous germ line tissues. To this …

[PDF][PDF] ATLAS: a system to selectively identify human-specific L1 insertions

RM Badge, RS Alisch, JV Moran - The American Journal of Human …, 2003 - cell.com
Retrotransposition of L1 LINEs (long interspersed elements) continues to sculpt the human
genome. However, because recent insertions are dimorphic, they are not fully represented …

Allelic variation of HERV-K (HML-2) endogenous retroviral elements in human populations

C Macfarlane, P Simmonds - Journal of molecular evolution, 2004 - Springer
Human endogenous retroviruses (HERVs) are the remnants of ancient germ cell infection by
exogenous retroviruses and occupy up to 8% of the human genome. It has been suggested …

A new family of chimeric retrotranscripts formed by a full copy of U6 small nuclear RNA fused to the 3′ terminus of l1

A Buzdin, S Ustyugova, E Gogvadze, T Vinogradova… - Genomics, 2002 - Elsevier
Long interspersed nuclear elements (LINE-1, L1) constitute a large family of mammalian
retrotransposons that have been replicating and evolving in mammals for more than 100 …

LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells

RB Jones, H Song, Y Xu, KE Garrison… - Journal of …, 2013 - Am Soc Microbiol
Type 1 long-interspersed nuclear elements (L1s) are autonomous retrotransposable
elements that retain the potential for activity in the human genome but are suppressed by …