Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …

Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Abstract The Wound Healing Foundation (WHF) recognised a need for an unbiased
consensus on the best treatment of chronic wounds. A panel of 13 experts were invited to a …

The treatment of diabetic wounds remains challenging due to the excess levels of oxidative
stress, vulnerability to bacterial infection, and persistent inflammation response during …

The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

Diabetic foot ulcers (DFUs) are a life-threatening disease that often result in lower limb
amputations and a shortened lifespan. However, molecular mechanisms contributing to the …

Skin is the largest organ in the human body, and the interplay between the environment
factors and human skin leads to some skin diseases, such as acne, psoriasis, and atopic …

The skin microbiome is an ecosystem comprised of a multitude of microbial species
interacting with their surroundings, including other microbes and host epithelial and immune …

Metagenomic sequencing for infectious disease diagnostics is an important tool that holds
promise for use in the clinical laboratory. Challenges for implementation so far include high …