Cancer is a complex disease involving numerous biological processes, which can exist in
parallel, can be complementary, or are engaged when needed and as such can replace …

Surgical resection is an important avenue for cancer treatment, which, in most cases, can
effectively alleviate the patient symptoms. However, accumulating evidence has …

Tumor cells display progressive changes in metabolism that correlate with malignancy,
including development of a lipogenic phenotype. How stored fats are liberated and …

Surgical excision is the mainstay of treatment for potentially curable solid tumours.
Metastatic disease is the most important cause of cancer-related death in these patients. The …

Lipidomics has been proving that membrane lipids play a crucial role in several cell
functions and are involved in several pathologies, including cancer. In fact, beyond a …

Nowadays we understand cell membranes not as a simple double lipid layer but as a
collection of complex and dynamic protein–lipid structures and microdomains that serve as …

Cancer cells couple heightened lipogenesis with lipolysis to produce fatty acid networks that
support malignancy. Monoacylglycerol lipase (MAGL) plays a principal role in this process …

Although most drugs bind to proteins and regulate their activity, some drugs act through a
new therapeutic approach called membrane-lipid therapy and bind to lipids, thus modulating …

The immediate perioperative period (days before and after surgery) is hypothesized to be
crucial in determining long-term cancer outcomes: during this short period, numerous …

Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …