Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

Ionic liquids in pharmaceutical industry: A systematic review on applications and future perspectives

W Zhuang, K Hachem, D Bokov, MJ Ansari… - Journal of Molecular …, 2022 - Elsevier
Ionic liquids (ILs) have demonstrated incredible potential of application in various industries
such as pharmaceutics. Appropriate utilization of ILs in the pharmaceutical industry can be a …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients

X Wu, Q Zhu, Z Chen, W Wu, Y Lu, J Qi - Journal of Controlled Release, 2021 - Elsevier
Ionic liquids (ILs) have been widely used in biomedical and pharmaceutical fields as
solvents or permeation enhancers. Recently, more and more researchers focused on …

Review of ionic liquid and ionogel-based biomaterials for advanced drug delivery

M Kuddushi, BB Xu, N Malek, X Zhang - Advances in Colloid and Interface …, 2024 - Elsevier
Ionic liquids (ILs) play a crucial role in the design of novel materials. The ionic nature of ILs
provides numerous advantages in drug delivery, acting as a green solvent or active …

[HTML][HTML] Synthesis and antibacterial activity of ionic liquids and organic salts based on penicillin g and amoxicillin hydrolysate derivatives against resistant bacteria

R Ferraz, D Silva, AR Dias, V Dias, MM Santos… - Pharmaceutics, 2020 - mdpi.com
The preparation and characterization of ionic liquids and organic salts (OSILs) that contain
anionic penicillin G [secoPen] and amoxicillin [seco-Amx] hydrolysate derivatives and their …

Active pharmaceutical ingredients (APIs) in ionic liquids: An effective approach for API physiochemical parameter optimization

M Handa, WH Almalki, R Shukla, O Afzal… - Drug Discovery …, 2022 - Elsevier
Highlights•Ionic liquids (ILs) are ions-based substances with melting points below 100
C.•Versatile nature and properties of ILs made it as solvent and designer …

Applications of phosphonium-based ionic liquids in chemical processes

S Khazalpour, M Yarie, E Kianpour, A Amani… - Journal of the Iranian …, 2020 - Springer
Among ionic liquids, phosphonium-based ionic liquids (PILs) are quite elegant. These
categories of ionic liquids represent some merits over other types of ionic liquids such as …

Advances in ionic liquids as future anti-cancer drugs

I Ali, M Hozaifa, S Ali, A Malik, M Locatelli - Journal of Molecular Liquids, 2023 - Elsevier
Ionic liquids are a very important class of molecules being used in a wide range of
applications. Recently, ionic liquids have been tested as anti-cancer agents and found …