The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

WHO estimated that nearly 1 million people become infected every day with any of four
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …

Current practice in the normalization of microbiome count data is inefficient in the statistical
sense. For apparently historical reasons, the common approach is either to use simple …

A noticeable part of the microbiome literature, especially that working with low-biomass
samples, is plagued by reagent contamination. Here we describe visual, statistical …

To what extent do host genetics control the composition of the gut microbiome? Studies
comparing the gut microbiota in human twins and across inbred mouse lines have yielded …

The human genome has been referred to as the blueprint of human biology. In this review
we consider an essential but largely ignored overlay to that blueprint, the human …

Background Bacterial vaginosis (BV) is a common condition that is associated with
numerous adverse health outcomes and is characterized by poorly understood changes in …

Bacterial vaginosis (BV) is the most common vaginal dysbiosis to affect women globally, yet
an unacceptably high proportion of women experience BV recurrence within 6 months of …

Owing to the fact that there are more microbial than human cells in our body and that
humans contain more microbial than human genes, the microbiome has huge potential to …

Previous studies using culture-based methods suggested an association between
constipation and altered abundance of certain taxa of the colonic microbiome. We aim to …