The global human gut microbiome: genes, lifestyles, and diet

M Parizadeh, MC Arrieta - Trends in Molecular Medicine, 2023 - cell.com
A growing number of human gut microbiome studies consistently describe differences
between human populations. Here, we review how factors related to host genetics, ethnicity …

The pathobiology of human fungal infections

GD Brown, ER Ballou, S Bates, EM Bignell… - Nature Reviews …, 2024 - nature.com
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

A probiotic nanozyme hydrogel regulates vaginal microenvironment for Candida vaginitis therapy

G Wei, Q Liu, X Wang, Z Zhou, X Zhao, W Zhou… - Science …, 2023 - science.org
Molecular therapeutics are limited for Candida vaginitis because they damage normal cells
and tissues of vagina, aggravating the imbalance of vaginal microbiota and increasing the …

Commensal fungi in intestinal health and disease

KS Ost, JL Round - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
The microbiota is known to influence several facets of mammalian development, digestion
and disease. Most studies of the microbiota have focused on the bacterial component, but …

Candida–bacterial cross-kingdom interactions

KR Eichelberger, S Paul, BM Peters, JE Cassat - Trends in Microbiology, 2023 - cell.com
While the fungus Candida albicans is a common colonizer of healthy humans, it is also
responsible for mucosal infections and severe invasive disease. Understanding the …

Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions

B Seelbinder, Z Lohinai, R Vazquez-Uribe… - Nature …, 2023 - nature.com
Candida species overgrowth in the human gut is considered a prerequisite for invasive
candidiasis, but our understanding of gut bacteria promoting or restricting this overgrowth is …

From intestinal colonization to systemic infections: Candida albicans translocation and dissemination

JL Sprague, L Kasper, B Hube - Gut Microbes, 2022 - Taylor & Francis
Candida species are the most prevalent cause of invasive fungal infections, of which
Candida albicans is the most common. Translocation across the epithelial barrier into the …

Lactobacillus species do not produce 1-acetyl-β-carboline

T Herraiz, A Sánchez-Arroyo, B de Las Rivas… - Nature …, 2024 - nature.com
In a recent article entitled “A small molecule produced by Lactobacillus species blocks
Candida albicans filamentation by inhibiting DYRK1-family kinase”, MacAlpine et al. 1 …

Metagenomics and metabolomics approaches in the study of Candida albicans colonization of host niches: a framework for finding microbiome-based antifungal …

M Delavy, N Sertour, C d'Enfert, ME Bougnoux - Trends in Microbiology, 2023 - cell.com
In silico and experimental approaches have allowed an ever-growing understanding of the
interactions within the microbiota. For instance, recently acquired data have increased …

The interactions of Candida albicans with gut bacteria: a new strategy to prevent and treat invasive intestinal candidiasis

F Wang, Z Wang, J Tang - Gut Pathogens, 2023 - Springer
Background The gut microbiota plays an important role in human health, as it can affect host
immunity and susceptibility to infectious diseases. Invasive intestinal candidiasis is strongly …