Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in
part can become irreversible to conventional therapies, defining the concept of airway …

Background In some patients with moderate-to-severe asthma, particularly those with
noneosinophilic inflammation, the disease remains uncontrolled. This trial evaluated the …

The main function of the lung is to perform gas exchange while maintaining lung
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …

Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …

Recent years have seen a marked increase in our understanding of innate lymphoid cells
(ILCs). ILCs can be classified into different groups based on their similarity to T cell subsets …

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …

abstract Bronchial asthma is characterized by persistent cough, increased sputum, and
repeated wheezing. The pathophysiology underlying these symptoms is the hyper …

Background Thymic stromal lymphopoietin (TSLP), an epithelial upstream cytokine, initiates
production of type 2 cytokines with eosinophilia and possibly airway hyperresponsiveness …

The discovery of IgE represented a major breakthrough in allergy and asthma research,
whereas the clinical interest given to IgE in asthma has been blurred until the arrival of anti …