Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …

Importance Mortality among people with opioid dependence is higher than that of the
general population. Opioid agonist treatment (OAT) is an effective treatment for opioid …

Abstract Background Since 2010, Black persons in the United States have had a greater
increase in opioid overdose–related mortality than other groups, but national-level evidence …

Importance Although clinical trials demonstrate the superior effectiveness of medication for
opioid use disorder (MOUD) compared with nonpharmacologic treatment, national data on …

Background: Opioid overdose survivors have an increased risk for death. Whether use of
medications for opioid use disorder (MOUD) after overdose is associated with mortality is not …

Stigma as a fundamental hindrance to the United States opioid overdose crisis response |
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We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

On October 30 and 31, 2018, the Committee on Medication-Assisted Treatment (MAT) for
Opioid Use Disorder (OUD) held a 1.5-day workshop in Washington, DC. To support the …

Abstract In 2022, 81,806 opioid-involved overdose deaths were reported in the United
States, more than in any previous year. Medications for opioid use disorder (OUD) …