Neuroprotective potential of chrysin in Parkinson's disease: Molecular mechanisms and clinical implications

E Angelopoulou, ES Pyrgelis, C Piperi - Neurochemistry international, 2020 - Elsevier
Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with
current treatment being mainly symptomatic and often accompanied by serious side effects …

Peripheral inflammation induces neuroinflammation that alters neurotransmission and cognitive and motor function in hepatic encephalopathy: Underlying …

A Cabrera‐Pastor, M Llansola, C Montoliu… - Acta …, 2019 - Wiley Online Library
Several million patients with liver cirrhosis suffer minimal hepatic encephalopathy (MHE),
with mild cognitive and coordination impairments that reduce their quality of life and life …

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction …

HMA Khalil, HA Eliwa, RA El-Shiekh… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Ashwagandha (ASH) is one of the medicinal plants used
in traditional Indian, Ayurvedic, and Unani medicines for their broad range of …

Thymol ameliorated neurotoxicity and cognitive deterioration in a thioacetamide-induced hepatic encephalopathy rat model; involvement of the BDNF/CREB signaling …

HA Ogaly, RF Abdel-Rahman, MAE Mohamed… - Food & Function, 2022 - pubs.rsc.org
In the present study, we aimed to delineate the neuroprotective potential of thymol (THY)
against neurotoxicity and cognitive deterioration induced by thioacetamide (TAA) in an …

Hepatoprotective and cognitive-enhancing effects of hesperidin against thioacetamide-induced hepatic encephalopathy in rats

NFA El-Magd, DH El-Kashef, M El-Sherbiny, SM Eraky - Life Sciences, 2023 - Elsevier
Hepatic encephalopathy (HE) is a serious neurological disorder which might occur in both
acute and chronic liver injury. Aims: This study was carried out to explore the protective …

Syringic acid protects against thioacetamide-induced hepatic encephalopathy: behavioral, biochemical, and molecular evidence

IF Okkay, U Okkay, OL Gundogdu, C Bayram… - Neuroscience …, 2022 - Elsevier
The objective of this study was to elucidate the effects of syringic acid on thioacetamide-
induced hepatic encephalopathy which is a complex serious syndrome with …

Ameliorative impacts of chrysin against gibberellic acid-induced liver and kidney damage through the regulation of antioxidants, oxidative stress, inflammatory …

MM Soliman, A Aldhahrani, A Gaber… - Toxicology …, 2022 - academic.oup.com
Abstract Gibberellic acid (GA3), a widely known plant growth regulator, has been mostly
used in agriculture. Little is known regarding its toxicity or the impact of its metabolic …

The protective effects of chrysin on cadmium-induced pulmonary toxicity; a multi-biomarker approach

N Akaras, M Ileriturk, C Gur, S Kucukler, M Oz… - … Science and Pollution …, 2023 - Springer
This study aimed to determine the potential protective effects of chrysin (CHR) on
experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into …

Lactoferrin averts neurological and behavioral impairments of thioacetamide-induced hepatic encephalopathy in rats via modulating HGMB1/TLR-4/MyD88/Nrf2 …

RM Essam, MA Saadawy, M Gamal, RM Abdelsalam… - …, 2023 - Elsevier
Hepatic encephalopathy (HE) is a life-threatening disease caused by acute or chronic liver
failure manifested by aberrant CNS changes. In the present study, we aimed to explore the …

A comprehensive review on hepatoprotective and nephroprotective activities of chrysin against various drugs and toxic agents

RB Pingili, AK Pawar, SR Challa, T Kodali… - Chemico-biological …, 2019 - Elsevier
Chrysin belongs to the flavonoids and has been used as traditional medicine from ancient
and has been reported to exhibit a wide range of pharmacological properties. The …