Intracellular peptides in cell biology and pharmacology
Intracellular peptides are produced by proteasomes following degradation of nuclear,
cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases …
cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases …
Hemopressin as a breakthrough for the cannabinoid field
Hemopressin (PVNFKFLSH in rats, and PVNFKLLSH in humans and mice), a fragment
derived from the α-chain of hemoglobin, was the first peptide described to have type 1 …
derived from the α-chain of hemoglobin, was the first peptide described to have type 1 …
New insights into peptide cannabinoids: structure, biosynthesis and signaling
A Riquelme-Sandoval, CO de Sá-Ferreira… - Frontiers in …, 2020 - frontiersin.org
Classically, the endocannabinoid system (ECS) consists of endogenous lipids, of which the
best known are anandamide (AEA) and 2 arachidonoylglycerol (2-AG), their enzyme …
best known are anandamide (AEA) and 2 arachidonoylglycerol (2-AG), their enzyme …
Signaling molecules targeting cannabinoid receptors: Hemopressin and related peptides
F Wei, L Zhao, Y Jing - Neuropeptides, 2020 - Elsevier
Cannabinoid receptors (CBRs) are part of the endocannabinoid system, which is involved in
various physiological processes such as nociception, inflammation, appetite, stress, and …
various physiological processes such as nociception, inflammation, appetite, stress, and …
Investigation of receptor binding and functional characteristics of hemopressin (1–7)
The orally active, α-hemoglobin derived hemopressin (PVNFKFLSH, Hp (1–9)) and its
truncated (PVNFKFL, Hp (1–7) and PVNFKF, Hp (1–6)) and extended ((R) VDPVNFKFLSH …
truncated (PVNFKFL, Hp (1–7) and PVNFKF, Hp (1–6)) and extended ((R) VDPVNFKFLSH …
VF-13, a chimeric peptide of VD-hemopressin (α) and neuropeptide VF, produces potent antinociception with reduced cannabinoid-related side effects
B Xu, J Xiao, K Xu, Q Zhang, D Chen, R Zhang… - …, 2020 - Elsevier
Pharmacological evidence indicated a functional interaction between neuropeptide FF
(NPFF) and cannabinoid systems, and the cannabinoids combined with the NPFF receptor …
(NPFF) and cannabinoid systems, and the cannabinoids combined with the NPFF receptor …
[HTML][HTML] Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice
S Glasmacher, J Gertsch - Advances in biological regulation, 2021 - Elsevier
Abstract Hemopressins ((x)-PVNFKLLSH) or peptide endocannabinoids (pepcans) can bind
to cannabinoid receptors. RVD-hemopressin (pepcan-12) was shown to act as endogenous …
to cannabinoid receptors. RVD-hemopressin (pepcan-12) was shown to act as endogenous …
Targeting the cannabinoid and mu opioid receptors with heterodimerized and allosteric ligands
S Dvorácskó - 2019 - search.proquest.com
Two series of bivalent compounds containing an opioid (oxycodone or Tyr-D-Ala-Gly-Phe)
and a cannabinoid (JWH-018) pharmacophore were designed, synthesized and …
and a cannabinoid (JWH-018) pharmacophore were designed, synthesized and …
[引用][C] Sıçanlarda penisilinle oluşturulan epileptiform aktivite üzerine hemopressinin rolü
H Aygün - platform.almanhal.com
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