Lysosomes are degradative organelles essential for cell homeostasis that regulate a variety
of processes, from calcium signaling and nutrient responses to autophagic degradation of …

Cathepsin B (CTSB), a lysosomal cysteine protease, plays an important role in human
physiology and pathology. CTSB is associated with various human diseases, and its …

This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

In this work, five naphthalimide-modified half-sandwich iridium and ruthenium complexes
([(η 5-Cp x) Ir (NˆN) Cl] PF 6,[(η 6-p-cym) Ru (NˆN) Cl] PF 6) have been presented. The …

Cysteine cathepsins are primarily involved in the degradation and recycling of proteins in
endo-lysosomal compartments but are also gaining recognition as pivotal proteolytic …

Four bichromophoric cyclometalated iridium complexes were synthesized and fully
characterized. Their antiproliferative capacity against A549, HepG2 cells and HeLa cells as …

Two rhodium complexes Rh1 and Rh2 with isoquinoline derivatives were synthesized and
characterized. Both complexes displayed strong anticancer activity against various cancer …

Natural products can be a source of biomolecules with antioxidant activity which are able to
prevent oxidative stress‐induced diseases and show antitumor activity, making them …

The global incidence of cancer is rising rapidly and continues to be one of the leading
causes of death in the world. Melanoma deserves special attention since it represents one of …

Phytochemical studies are seeking new alternatives to prevent or treat cancer, including
different types of leukemias. Campomanesia adamantium, commonly known as guavira or …