Obesity is a major global health problem determined by heredity and environment, and its
incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut …

The assembly of microbial communities within the gastrointestinal tract during early life plays
a critical role in immune, endocrine, metabolic, and other host developmental pathways …

To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …

The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated …

From asthma and heart disease to diabetes and obesity, the human microbiome plays a role
in the pathogenesis of each chronic health condition plaguing today's society. Recent work …

Individuals who are minoritized as a result of race, sexual identity, gender, or socioeconomic
status experience a higher prevalence of many diseases. Understanding the biological …

Maternal obesity is associated with increased risk for offspring obesity and non-alcoholic
fatty liver disease (NAFLD), but the causal drivers of this association are unclear. Early …

Trillions of microbes reside in the human body and participate in multiple physiological and
pathophysiological processes that affect host health throughout the life cycle. The …

Dysbiosis of gut microbiota has been retrospectively linked to autism spectrum disorders but
the temporal association between gut microbiota and early neurodevelopment in healthy …

Early life, including the establishment of the intestinal microbiome, represents a critical
window of growth and development. Postnatal factors affecting the microbiome, including …