Photodynamic therapy (PDT) is a promising cancer treatment which involves a
photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which …

The search for innovative anti-cancer drugs remains a challenge. Over the past three
decades, antibodies have emerged as an essential asset in successful cancer therapy. The …

Reliable, specific polyclonal and monoclonal antibodies are important tools in research and
medicine. However, the discovery of antibodies against their targets in their native forms is …

Phage display technology (PD) is a powerful technique for the generation of tumor-targeting
antibodies. However, there are a number of different selection methods established in …

Angiogenesis, as a tumor hallmark, plays an important role in the growth and development
of the tumor vasculature system. There is a huge amount of evidence suggesting that the …

Antibody phage display selection on cells is a powerful tool to generate highly specific
antibodies recognizing a target in its cell bound conformation. Unlike phage display …

Numerous potential drug targets, including G-protein-coupled receptors and ion channel
proteins, reside on the cell surface as multi-pass membrane proteins. Unfortunately, despite …

Purpose: Production of functional recombinant antibody fragments in the periplasm of E. coli
is a prerequisite step to achieve sufficient reagent for preclinical studies. Thus, the cost …

Phage display technology is a widely used practical tool for isolating binding molecules
against the desired targets in phage libraries. In the case of targeting the membrane protein …

In this research, four novel and sensitive immunosensors for electrochemical determination
of G17-Gly were designed based on signal amplification and tailor-made recombinant …