The microbiota-gut-brain axis in sleep disorders

Z Wang, Z Wang, T Lu, W Chen, W Yan, K Yuan… - Sleep medicine …, 2022 - Elsevier
Sleep is a complex physiological process and is a critical determinant of physical and
mental health. In the past decades, significant progress has been made in understanding …

[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system

TCA Hitch, LJ Hall, SK Walsh, GE Leventhal, E Slack… - Mucosal …, 2022 - Elsevier
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

S Zuffa, R Schmid, A Bauermeister, PW P. Gomes… - Nature …, 2024 - nature.com
Abstract microbeMASST, a taxonomically informed mass spectrometry (MS) search tool,
tackles limited microbial metabolite annotation in untargeted metabolomics experiments …

Cardiometabolic health, diet and the gut microbiome: a meta-omics perspective

M Valles-Colomer, C Menni, SE Berry, AM Valdes… - Nature Medicine, 2023 - nature.com
Cardiometabolic diseases have become a leading cause of morbidity and mortality globally.
They have been tightly linked to microbiome taxonomic and functional composition, with diet …

Gut microbiota regulates blood‐cerebrospinal fluid barrier function and Aβ pathology

J Xie, A Bruggeman, C De Nolf… - The EMBO …, 2023 - embopress.org
Accumulating evidence indicates that gut microbiota dysbiosis is associated with increased
blood–brain barrier (BBB) permeability and contributes to Alzheimer's disease (AD) …

Gut bacterial nutrient preferences quantified in vivo

X Zeng, X Xing, M Gupta, FC Keber, JG Lopez… - Cell, 2022 - cell.com
Great progress has been made in understanding gut microbiomes' products and their effects
on health and disease. Less attention, however, has been given to the inputs that gut …

Multi-omics profiles of the intestinal microbiome in irritable bowel syndrome and its bowel habit subtypes

JP Jacobs, V Lagishetty, MC Hauer, JS Labus… - Microbiome, 2023 - Springer
Background Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is
thought to involve alterations in the gut microbiome, but robust microbial signatures have …

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Aging microbiota-gut-brain axis in stroke risk and outcome

P Honarpisheh, RM Bryan, LD McCullough - Circulation research, 2022 - Am Heart Assoc
The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …

Boundaries and integration between microbiota, the nervous system, and immunity

AJ Macpherson, V Pachnis, M Prinz - Immunity, 2023 - cell.com
The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …