Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

Epidemiology of Candida species infections in critically ill non-immunosuppressed patients

P Eggimann, J Garbino, D Pittet - The Lancet infectious diseases, 2003 - thelancet.com
A substantial proportion of patients become colonised with Candida spp during hospital
stay, but only few subsequently develop severe infection. Clinical signs of severe infection …

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

[PDF][PDF] Antimicrobial and antiviral activity of hydrolysable tannins

P Buzzini, P Arapitsas, M Goretti, E Branda… - Mini-Reviews in …, 2008 - academia.edu
Hydrolysable tannins (HTs), secondary metabolites widely distributed in the plant kingdom,
are generally multiple esters of gallic acid with glucose. HTs have been shown to be …

Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

D Sanglard, F Ischer, T Parkinson… - Antimicrobial agents …, 2003 - Am Soc Microbiol
The role of sterol mutations in the resistance of Candida albicans to antifungal agents has
not been thoroughly investigated. Previous work reported that clinical C. albicans strains …

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

D Sanglard, A Coste, S Ferrari - FEMS yeast research, 2009 - academic.oup.com
Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution.
Some fungal species may interact with other life forms (plants, insects, mammals), but are …

Application of hydrophobic deep eutectic solvent as the carrier for ferrofluid: a novel strategy for pre-concentration and determination of mefenamic acid in human …

EA Dil, M Ghaedi, A Asfaram - Talanta, 2019 - Elsevier
In this study, ferrofluid of magnetic nanoparticles, oleic acid (OA), combined with
hydrophobic deep eutectic solvent (Fe 3 O 4 [iron oxide]-OA-DES) was prepared and …

Candida glabrata Biofilms: How Far Have We Come?

CF Rodrigues, ME Rodrigues, S Silva, M Henriques - Journal of fungi, 2017 - mdpi.com
Infections caused by Candida species have been increasing in the last decades and can
result in local or systemic infections, with high morbidity and mortality. After Candida …

Pathogenicity and drug resistance in Candida albicans and other yeast species

N Mishra, T Prasad, N Sharma, A Payasi… - Acta microbiologica et …, 2007 - akjournals.com
Pathogenic yeasts from the genus Candida can cause serious infection in humans
particularly, in immunocompromised patients and are now recognized as major agents of …

Rapid identification of fungi by sequencing the ITS1 and ITS2 regions using an automated capillary electrophoresis system

TM Pryce, S Palladino, ID Kay, GW Coombs - Medical mycology, 2003 - academic.oup.com
We developed a standardized DNA sequence-based approach for the accurate and timely
identification of medically important fungi by sequencing polymerase chain reaction (PCR) …