Pharmacokinetics and biosafety evaluation of a veterinary drug florfenicol in rainbow trout, Oncorhynchus mykiss (Walbaum 1792) as a model cultivable fish species …

SK Mallik, N Shahi, R Pathak, K Kala, PK Patil… - Frontiers in …, 2023 - frontiersin.org
In two experimental trials; florfenicol pharmacokinetics following a single dose oral
administration at 15 mg kg− 1 fish body weight and biosafety through extended medicated …

Combination of antimicrobials as an approach to reduce their application in aquaculture: Emphasis on the use of thiamphenicol/florfenicol against Aeromonas …

IM Assane, KS Gozi, GMR Valladão, F Pilarski - Aquaculture, 2019 - Elsevier
Individual minimum inhibitory and bactericidal concentrations (MIC and MBC) of
thiamphenicol (TAP), florfenicol (FFC) and oxytetracycline (OTC) were determined for 49 …

Temperature-dependent pharmacokinetics of florfenicol in Nile tilapia (Oreochromis niloticus) following single oral and intravenous administration

T Rairat, CY Hsieh, W Thongpiam, CH Sung, CC Chou - Aquaculture, 2019 - Elsevier
Temperature-dependent pharmacokinetics (PK) have rarely been reported in tilapia despite
there are popularly cultured worldwide, ranging from tropical to temperate climates. The …

Effects of Florfenicol on Intestinal Histology, Apoptosis and Gut Microbiota of Chinese Mitten Crab (Eriocheir sinensis)

X Guo, Z Qian, Q Pan, Y Hu, W Mei, X Xing… - International Journal of …, 2023 - mdpi.com
Excessive use of antibiotics in aquaculture causes residues in aquatic animal products and
harms human health. However, knowledge of florfenicol (FF) toxicology on gut health and …

Artemisinin alters disposition regularities of enrofloxacin and its metabolite ciprofloxacin in channel catfish (Ictalurus punetaus) following combined oral administration

Y Liu, G Zhang, Y Yang, S Zhou, J Dong, Q Yang, N Xu… - Aquaculture, 2023 - Elsevier
The aim of this investigation was to explore the effect of artemisinin (ART) on
pharmacokinetic (PK) and tissue distribution characteristics of enrofloxacin (ENR) and …

Pharmacokinetics, optimal dosages and withdrawal time of florfenicol in Asian seabass (Lates calcarifer) after oral administration via medicated feed

T Rairat, S Kumphaphat, N Chuchird… - Journal of Fish …, 2023 - Wiley Online Library
Asian seabass (Lates calcarifer) is an economically important fish in Asian and Australian
markets, but few pharmacokinetic (PK) data of antimicrobial drugs in this species is …

Evaluation of absorption and depletion of florfenicol in European seabass Dicentrarchus labrax

D Kogiannou, C Nikoloudaki… - Veterinary Medicine …, 2021 - Wiley Online Library
The pharmacokinetic properties and residue elimination of florfenicol (FLO) and its amine
were investigated in European seabass Dicentrarchus labrax at 24° C. The trial mainly …

Depletion study and estimation of withdrawal periods for florfenicol and florfenicol amine in pacu (Piaractus mesopotamicus)

TV Marques, JAR Paschoal, RSC Barone… - Aquaculture …, 2018 - Wiley Online Library
The intensive production of farmed fish is at a global all‐time high, and the control of
bacteria proliferation in fish farms requires the frequent use of antimicrobials. This practice …

Optimization of florfenicol dose against Piscirickettsia salmonis in Salmo salar through PK/PD studies

B San Martin, M Fresno, J Cornejo, M Godoy, R Ibarra… - PLoS …, 2019 - journals.plos.org
Salmonid Rickettsial Septicemia (SRS) is the disease of greatest economic importance in
the Chilean salmon farming industry, causing high mortality in fish during the final stage of …

Pharmacokinetics of florfenicol and thiamphenicol after single oral and intravenous, as well as multiple oral administrations to geese

M Tikhomirov, B Poźniak, A Smutkiewicz… - British Poultry …, 2021 - Taylor & Francis
This study evaluated the pharmacokinetic profiles of florfenicol (FF) and thiamphenicol (TP),
which are synthetic bacteriostatic antimicrobial drugs, in geese after a single intravenous or …