The pathogenesis of psoriasis can be explained by dysregulation of immunological cell
function as well as keratinocyte proliferation/differentiation. Recently, the immunological …

The NF-κB family of inducible transcription factors is activated in response to a variety of
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …

Gut microbiota-mediated secondary bile acids (BAs) play an important role in energy
balance and host metabolism via G protein-coupled receptors and/or nuclear receptors …

NF-κB (nuclear factor kappa B) family transcription factors are master regulators of immune
and inflammatory processes in response to both injury and infection. In the latent state, NF …

Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

The ability to sense and adjust to the environment is crucial to life. For multicellular
organisms, the ability to respond to external changes is essential not only for survival but …

▪ Abstract The transcription factor NF-κB, more than a decade after its discovery, remains an
exciting and active area of study. The involvement of NF-κB in the expression of numerous …

NF-kappa B is a ubiquitous transcription factor. Nevertheless, its properties seem to be most
extensively exploited in cells of the immune system. Among these properties are NF-kappa …

Hydrogen peroxide and oxygen radicals are agents commonly produced during
inflammatory processes. In this study, we show that micromolar concentrations of H2O2 can …

The possibility that lipid-induced insulin resistance in human muscle is related to alterations
in diacylglycerol (DAG)/protein kinase C (PKC) signaling was investigated in normal …