Membrane fission by dynamin: what we know and what we need to know

B Antonny, C Burd, P De Camilli, E Chen… - The EMBO …, 2016 - embopress.org
The large GTP ase dynamin is the first protein shown to catalyze membrane fission.
Dynamin and its related proteins are essential to many cell functions, from endocytosis to …

Animal Enterotoxigenic Escherichia coli

JD Dubreuil, RE Isaacson, DM Schifferli - EcoSal Plus, 2016 - Am Soc Microbiol
Enterotoxigenic Escherichia coli (ETEC) is the most common cause of E. coli diarrhea in
farm animals. ETEC are characterized by the ability to produce two types of virulence factors …

[HTML][HTML] An expanded arsenal of immune systems that protect bacteria from phages

A Millman, S Melamed, A Leavitt, S Doron… - Cell host & …, 2022 - cell.com
Bacterial anti-phage systems are frequently clustered in microbial genomes, forming
defense islands. This property enabled the recent discovery of multiple defense systems …

Structural insights into the mechanism of dynamin superfamily proteins

JR Jimah, JE Hinshaw - Trends in Cell Biology, 2019 - cell.com
Dynamin superfamily proteins (DSPs) mediate membrane fission and fusion necessary for
endocytosis, organelle biogenesis and maintenance, as well as for bacterial cytokinesis …

Conservation of antiviral systems across domains of life reveals immune genes in humans

J Cury, M Haudiquet, VH Trejo, E Mordret… - Cell Host & Microbe, 2024 - cell.com
Deciphering the immune organization of eukaryotes is important for human health and for
understanding ecosystems. The recent discovery of antiphage systems revealed that various …

Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily

O Daumke, GJK Praefcke - Biopolymers, 2016 - Wiley Online Library
Dynamin superfamily proteins are multidomain mechano‐chemical GTPases which are
implicated in nucleotide‐dependent membrane remodeling events. A prominent feature of …

Two dynamin-like proteins stabilize FtsZ rings during Streptomyces sporulation

S Schlimpert, S Wasserstrom… - Proceedings of the …, 2017 - National Acad Sciences
During sporulation, the filamentous bacteria Streptomyces undergo a massive cell division
event in which the synthesis of ladders of sporulation septa convert multigenomic hyphae …

Conservation of antiviral systems across domains of life reveals novel immune mechanisms in humans

J Cury, E Mordret, VH Trejo, F Tesson, G Ofir… - bioRxiv, 2022 - biorxiv.org
Viral infection is a common threat to prokaryotic and eukaryotic life, which has resulted in the
evolution of a myriad of antiviral systems. Some of these eukaryotic systems are thought to …

A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture

A Kumar, MO Gok, KN Nguyen, OM Connor, ML Reese… - Current Biology, 2024 - cell.com
Mitochondrial cristae architecture is crucial for optimal respiratory function of the organelle.
Cristae shape is maintained in part by the mitochondrial contact site and cristae organizing …

Mycobacterial dynamin-like protein IniA mediates membrane fission

M Wang, X Guo, X Yang, B Zhang, J Ren, A Liu… - Nature …, 2019 - nature.com
Mycobacterium tuberculosis infection remains a major threat to human health worldwide.
Drug treatments against tuberculosis (TB) induce expression of several mycobacterial …