Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications
Head and neck squamous cell carcinoma (HNSCC) are among the well-known neoplasms
originating in the oral cavity, pharynx, and larynx. Despite advancements in chemotherapy …
originating in the oral cavity, pharynx, and larynx. Despite advancements in chemotherapy …
Retracted: CRNDE promotes malignant progression of glioma by attenuating miR-384/PIWIL4/STAT3 Axis
J Zheng, X Liu, P Wang, Y Xue, J Ma, C Qu, Y Liu - Molecular therapy, 2016 - cell.com
Colorectal neoplasia differentially expressed (CRNDE) is the most upregulated long
noncoding RNA (lncRNA) in glioma. Herein, the function and potential molecular …
noncoding RNA (lncRNA) in glioma. Herein, the function and potential molecular …
Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer
W Weng, N Liu, Y Toiyama, M Kusunoki, T Nagasaka… - Molecular cancer, 2018 - Springer
Background Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be
important epigenetic regulators of gene expression in human cancers; however, their …
important epigenetic regulators of gene expression in human cancers; however, their …
piRNAs and PIWI proteins as diagnostic and prognostic markers of genitourinary cancers
K Hanusek, S Poletajew, P Kryst… - Biomolecules, 2022 - mdpi.com
piRNAs (PIWI-interacting RNAs) are small non-coding RNAs capable of regulation of
transposon and gene expression. piRNAs utilise multiple mechanisms to affect gene …
transposon and gene expression. piRNAs utilise multiple mechanisms to affect gene …
Circulating exosomal small RNAs are promising non‐invasive diagnostic biomarkers for gastric cancer
Dysregulation of small non‐coding RNA (ncRNA) is associated with various human
diseases including cancer. This study aimed to evaluate the circulating exosomal small …
diseases including cancer. This study aimed to evaluate the circulating exosomal small …
Somatic expression of piRNA and associated machinery in the mouse identifies short, tissue-specific piRNA
Piwi-interacting RNAs (piRNAs) are small non-coding RNAs that associate with PIWI
proteins for transposon silencing via DNA methylation and are highly expressed and …
proteins for transposon silencing via DNA methylation and are highly expressed and …
piR-651 promotes tumor formation in non-small cell lung carcinoma through the upregulation of cyclin D1 and CDK4
D Li, Y Luo, Y Gao, Y Yang… - International …, 2016 - spandidos-publications.com
Piwi-interacting RNAs (piRNAs or piRs) are a novel class of non-coding RNAs that
participate in germline development by silencing transposable elements and regulating …
participate in germline development by silencing transposable elements and regulating …
Prognosis of clear cell renal cell carcinoma patients stratified by age: A research relied on SEER database
Z Liao, D Wang, N Song, Y Xu, H Ge, Z Peng - Frontiers in oncology, 2022 - frontiersin.org
Objective Clear cell renal cell carcinoma may affect patients of any age. To date, there are
only a limited number of large data studies on renal clear cell carcinoma in different age …
only a limited number of large data studies on renal clear cell carcinoma in different age …
Decreased expression levels of PIWIL1, PIWIL2, and PIWIL4 are associated with worse survival in renal cell carcinoma patients
R Iliev, M Stanik, M Fedorko, A Poprach… - OncoTargets and …, 2016 - Taylor & Francis
Piwi-interacting RNAs (piRNAs) are a newly discovered class of small non-coding RNAs
involved in silencing of transposable elements and in sequence-specific chromatin …
involved in silencing of transposable elements and in sequence-specific chromatin …
Emerging roles for PIWI proteins in cancer
Y Tan, L Liu, M Liao, C Zhang, S Hu… - Acta biochimica et …, 2015 - academic.oup.com
It is generally accepted that PIWI proteins are predominately expressed in the germline but
absent in somatic tissues. Their best-characterized role is to suppress transposon …
absent in somatic tissues. Their best-characterized role is to suppress transposon …