Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …

Background Psychostimulant misuse is a continuously growing medical and social burden.
There is no evidence proving the efficacy of pharmacotherapy. Psychosocial interventions …

Introduction: Provisional estimates indicate that drug overdose deaths increased in 2019
after a slight decrease in 2018. In 2018, overdose deaths primarily involved opioids, with …

Abstract In the United States, combined stimulant/opioid overdose mortality has risen
dramatically over the last decade. These increases may particularly affect non-Hispanic …

Importance Despite high rates of drug overdose death among people experiencing
homelessness, patterns in drug overdose mortality, including the types of drugs implicated in …

Background Drug overdose deaths involving stimulants, including cocaine and
psychostimulants with abuse potential (eg, methamphetamine), have been increasing, partly …

Background Cocaine use contines to be a significant public health problem world‐wide.
However, despite substantial research efforts, no pharmacotherapies are approved for the …

The incidence of injection drug use–associated infective endocarditis has been increasing
rapidly over the last decade. Patients with drug use–associated infective endocarditis …

Drug markets are dynamic systems which change based on demand, competition,
legislation and revenue. Shifts that are not met with immediate and appropriate responses …

Recent attention has focused on the growing role of psychostimulants, such as
methamphetamine in overdose deaths. Methamphetamine is an addictive and potent …