TRPC channels: Structure, function, regulation and recent advances in small molecular probes
Transient receptor potential canonical (TRPC) channels constitute a group of receptor-
operated calcium-permeable nonselective cation channels of the TRP superfamily. The …
operated calcium-permeable nonselective cation channels of the TRP superfamily. The …
Transient receptor potential canonical (TRPC) channels: then and now
Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …
Store-operated calcium channels
AB Parekh, JW Putney Jr - Physiological reviews, 2005 - journals.physiology.org
In electrically nonexcitable cells, Ca2+ influx is essential for regulating a host of kinetically
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …
An introduction to TRP channels
IS Ramsey, M Delling, DE Clapham - Annu. Rev. Physiol., 2006 - annualreviews.org
▪ Abstract The aim of this review is to provide a basic framework for understanding the
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
[HTML][HTML] Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
T Hofmann, AG Obukhov, M Schaefer, C Harteneck… - Nature, 1999 - nature.com
Eukaryotic cells respond to many hormones and neurotransmitters with increased activity of
the enzyme phospholipase C and a subsequent rise in the concentration of intracellular free …
the enzyme phospholipase C and a subsequent rise in the concentration of intracellular free …
Transient receptor potential cation channels in disease
The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
[HTML][HTML] The TRP ion channel family
DE Clapham, LW Runnels, C Strübing - Nature Reviews Neuroscience, 2001 - nature.com
Mammalian homologues of the Drosophila transient receptor potential (TRP) channel gene
encode a family of at least 20 ion channel proteins. They are widely distributed in …
encode a family of at least 20 ion channel proteins. They are widely distributed in …
The TRP superfamily of cation channels
C Montell - Science's STKE, 2005 - science.org
The transient receptor potential (TRP) protein superfamily consists of a diverse group of
cation channels that bear structural similarities to Drosophila TRP. TRP channels play …
cation channels that bear structural similarities to Drosophila TRP. TRP channels play …
[HTML][HTML] OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
R Strotmann, C Harteneck, K Nunnenmacher… - Nature cell …, 2000 - nature.com
Ca 2+-permeable channels that are involved in the responses of mammalian cells to
changes in extracellular osmolarity have not been characterized at the molecular level. Here …
changes in extracellular osmolarity have not been characterized at the molecular level. Here …
TRP channels as potential drug targets
MM Moran - Annual review of pharmacology and toxicology, 2018 - annualreviews.org
The transient receptor potential (TRP) superfamily of channels comprises a diverse group of
cation channels. Four TRP channel subunits coassemble to form functional homo-or …
cation channels. Four TRP channel subunits coassemble to form functional homo-or …