Tranexamic acid use in the surgical arena: a narrative review
AM Mergoum, AS Mergoum, NJ Larson… - Journal of Surgical …, 2024 - Elsevier
Introduction Tranexamic acid (TXA) is a potent antifibrinolytic drug that inhibits the activation
of plasmin by plasminogen. While not a new medication, TXA has quickly gained traction …
of plasmin by plasminogen. While not a new medication, TXA has quickly gained traction …
A literature review assessing the perioperative efficacy and safety of tranexamic acid in elective total hip and knee arthroplasty in UK practice
R Patel, S Golding, R Nandra… - Journal of Perioperative …, 2024 - journals.sagepub.com
Hip and knee arthroplasty are frequently associated with significant blood loss, often
necessitating blood transfusions. A variety of methods are employed to minimise blood loss …
necessitating blood transfusions. A variety of methods are employed to minimise blood loss …
Tranexamic acid may benefit patients with preexisting thromboembolic risk undergoing total joint arthroplasty: a systematic review and meta-analysis
X Dang, M Liu, Q Yang, J Jiang, Y Liu… - EFORT Open …, 2024 - eor.bioscientifica.com
Purpose This study sought to determine if the use of tranexamic acid (TXA) in preexisting
thromboembolic risk patients undergoing total joint arthroplasty (TJA) was linked to an …
thromboembolic risk patients undergoing total joint arthroplasty (TJA) was linked to an …
Tranexamic Acid Is Safe in Arthroplasty Patients Who Have a History of Venous Thromboembolism: An Analysis Accounting for Surgeon Selection Bias
RC Palmer, SS Telang, J Wier, A Dobitsch… - The Journal of …, 2024 - Elsevier
Background Retrospective data supporting the use of tranexamic acid (TXA) among high-
risk total joint arthroplasty (TJA) patients are limited by surgeon selection bias. This study …
risk total joint arthroplasty (TJA) patients are limited by surgeon selection bias. This study …
The Use of Tranexamic Acid for Primary Prophylaxis of Heterotopic Ossification Following Total Hip Arthroplasty
AH Johnson, JC Brennan, P Rana, JJ Turcotte… - The Journal of …, 2024 - Elsevier
Background Heterotopic ossification (HO) is a relatively common complication after total hip
arthroplasty (THA) and can range from a radiographic observation only to severely disabling …
arthroplasty (THA) and can range from a radiographic observation only to severely disabling …
Comparative effectiveness of combined peri-articular and intra-articular injection versus intravenous and intra-articular injection of tranexamic acid in total knee …
P Pinsornsak, R Thaveekitikul, P Pinsornsak… - Archives of Orthopaedic …, 2024 - Springer
Materials and methods We conducted a double-blind, randomized controlled trial comparing
the use of PA+ IA TXA administration and IV+ IA TXA administration in 70 patients who were …
the use of PA+ IA TXA administration and IV+ IA TXA administration in 70 patients who were …
[HTML][HTML] Perioperative Tranexamic Acid Should Be Considered for Total Joint Arthroplasty Patients Receiving Apixaban for Thromboprophylaxis
S Telang, R Palmer, A Dobitsch, JR Ball… - Arthroplasty Today, 2024 - Elsevier
Background This study aims to investigate if the perioperative administration of tranexamic
acid (TXA) for total joint arthroplasty (TJA) patients receiving apixaban for …
acid (TXA) for total joint arthroplasty (TJA) patients receiving apixaban for …
What Are the Contraindications, if Any, for the Use of Tranexamic Acid During Knee or Hip Arthroplasty?
In 1962, a chemical compound, trans-4 aminomethylcyclohexane-1-carboxylic acid, was 29
developed by Utako and Shosuke Okamoto. This compound, which was renamed later as …
developed by Utako and Shosuke Okamoto. This compound, which was renamed later as …
The Impact of Tranexamic Acid on Blood Loss Management in Primary Total Knee Arthroplasty: A Comprehensive Review
S Sawant, SV Deshpande, H Wamborikar… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Total knee arthroplasty (TKA) is a widely performed surgical procedure to restore function
and relieve pain in patients with advanced knee arthritis. One of the key challenges in TKA is …
and relieve pain in patients with advanced knee arthritis. One of the key challenges in TKA is …