New perspectives in glutamate and anxiety
CR Bermudo-Soriano, MM Perez-Rodriguez… - Pharmacology …, 2012 - Elsevier
Anxiety and stress-related disorders, namely posttraumatic stress disorder (PTSD),
generalized anxiety disorder (GAD), obsessive–compulsive disorder (ODC), social and …
generalized anxiety disorder (GAD), obsessive–compulsive disorder (ODC), social and …
Aliphatic polyamines in physiology and diseases
D Ramani, JP De Bandt, L Cynober - Clinical nutrition, 2014 - Elsevier
Aliphatic polyamines are a family of polycationic molecules derived from decarboxylation of
the amino acid ornithine that classically comprise three molecules: putrescine, spermidine …
the amino acid ornithine that classically comprise three molecules: putrescine, spermidine …
Pharmacological alternatives for the treatment of neurodegenerative disorders: Wasp and bee venoms and their components as new neuroactive tools
Neurodegenerative diseases are relentlessly progressive, severely impacting affected
patients, families and society as a whole. Increased life expectancy has made these …
patients, families and society as a whole. Increased life expectancy has made these …
Calcium‐permeable AMPA receptors are involved in the induction and expression of l‐DOPA‐induced dyskinesia in Parkinson's disease
C Kobylecki, MA Cenci, AR Crossman… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 114, 409–511. Abstract Overactivity of striatal α‐amino‐3‐hydroxy‐5‐
methyl‐4‐isoxazolepropionic acid (AMPA) glutamate receptors is implicated in the …
methyl‐4‐isoxazolepropionic acid (AMPA) glutamate receptors is implicated in the …
Neurotoxins from invertebrates as anticonvulsants: from basic research to therapeutic application
MR Mortari, AOS Cunha, LB Ferreira… - Pharmacology & …, 2007 - Elsevier
Invertebrate venoms have attracted considerable interest as a potential source of bioactive
substances, especially neurotoxins. These molecules have proved to be extremely useful …
substances, especially neurotoxins. These molecules have proved to be extremely useful …
Targeting ionotropic receptors with polyamine-containing toxins☆
IR Mellor, PNR Usherwood - Toxicon, 2004 - Elsevier
This review summarises current knowledge of polyamine-containing spider toxins and their
interactions with ionotropic receptors of invertebrate and vertebrate excitable cells. Their …
interactions with ionotropic receptors of invertebrate and vertebrate excitable cells. Their …
Probing TARP modulation of AMPA receptor conductance with polyamine toxins
The properties of synaptic AMPA receptors (AMPARs) depend on their subunit composition
and association with transmembrane AMPAR regulatory proteins (TARPs). Although both …
and association with transmembrane AMPAR regulatory proteins (TARPs). Although both …
Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene–environment interactions with childhood/adolescent physical …
M Sokolowski, YJ Ben-Efraim, J Wasserman… - Molecular …, 2013 - nature.com
The complex etiology of suicidal behavior has frequently been investigated in relation to
monoaminergic neurotransmission, but other neurosystems have shown alterations as well …
monoaminergic neurotransmission, but other neurosystems have shown alterations as well …
Evidence of altered polyamine concentrations in cerebral cortex of suicide completers
GG Chen, LM Fiori, L Moquin, A Gratton… - …, 2010 - nature.com
Recent studies have implicated alterations in the expression of polyamine-related genes in
the brains of suicide completers including widespread downregulation of …
the brains of suicide completers including widespread downregulation of …
Design of antagonists for NMDA and AMPA receptors
KV Bolshakov, KH Kim, NN Potapjeva, VE Gmiro… - …, 2005 - Elsevier
Determinants of antagonism of NMDA and calcium permeable AMPA receptor channels by
organic cations were studied using several homologous series of mono-and dicationic …
organic cations were studied using several homologous series of mono-and dicationic …