Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …

Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …

While the overwhelming majority of wounds heal rapidly, a significant proportion fail to
progress through the wound‐healing process. These resultant chronic wounds cause …

Wound healing is the physiologic response to a disruption in normal skin architecture and
requires both spatial and temporal coordination of multiple cell types and cytokines. This …

Previously we developed and characterized a novel hydrogel film wound dressing
containing Sodium Alginate and Pectin loaded with Simvastatin with multi-functional …

Chronic wounds such as diabetic foot ulcers and venous leg ulcers place a significant
burden on the healthcare system and in some cases, have 5-year mortality rates …

Adipose tissue–derived stem cells (ASC s) are gaining increasing consideration in tissue
repair therapeutic application. Recent evidence indicates that ASC s enhance skin repair in …

One of the most common complications of diabetes is diabetic foot ulcer. Diabetic ulcers do
not heal easily due to diabetic neuropathy and reduced blood flow, and nonhealing ulcers …

Background Adipose-derived mesenchymal stem cells (ADSCs) are an important focus in
regenerative medicine. However, the biological function of ADSCs in the wound repair of …

A central feature of diabetic (Db) wounds is the persistence of chronic inflammation, which is
partly due to the prolonged presence of proinflammatory (M1) macrophages. Using in vivo …