Improving cerebrovascular function may be a key mechanism whereby a healthy lifestyle, of
which a healthy diet combined with increased physical activity levels is a cornerstone …

Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

Acute and chronic alcohol exposure significantly affect behavior but the underlying
neurobiological mechanisms are still poorly understood. Here, we used functional …

Respiratory challenge MRI is the modification of arterial oxygen (PaO 2) and/or carbon
dioxide (PaCO 2) concentration to induce a change in cerebral function or metabolism which …

Recent evidence identifies 12 potentially modifiable risk factors for dementia to which 40%
of dementia cases are attributed. While the recognition of these risk factors has paved the …

Alcohol abuse and dependence remain significant public health issues, and yet the brain
circuits that are involved in the rewarding effects of alcohol are poorly understood. One …

Opioids are important tools for pain management, but abuse can result in serious health
complications. Of these complications, respiratory depression that leads to brain hypoxia is …

Pueraria lobata is one of the most important medicinal herbs used traditionally in China.
According to Shanghan Lun (Treatise on Exogenous Febrile Disease), it has been used …

Alcohol intake leading to blood ethanol concentrations (BEC)≥ legal intoxication modifies
brain blood flow with increases in some regions and decreases in others. Brain regions …

Alcohol use disorder (AUD) is a global health concern associated with several
comorbidities. Various health problems related to AUD, such as cognitive deficits, have been …