Light-based vat-polymerization bioprinting

R Levato, O Dudaryeva… - Nature Reviews …, 2023 - nature.com
Light-based vat-polymerization bioprinting enables computer-aided patterning of 3D cell-
laden structures in a point-by-point, layer-by-layer or volumetric manner, using vat (vats) …

Multiphoton lithography as a promising tool for biomedical applications

C Greant, B Van Durme, J Van Hoorick… - Advanced Functional …, 2023 - Wiley Online Library
Multiphoton lithography (MPL) is a powerful and useful structuring tool capable of
generating 2D and 3D arbitrary micro‐and nanometer features of various materials with high …

3D microvascularized tissue models by laser‐based cavitation molding of collagen

A Enrico, D Voulgaris, R Östmans… - Advanced …, 2022 - Wiley Online Library
Abstract 3D tissue models recapitulating human physiology are important for fundamental
biomedical research, and they hold promise to become a new tool in drug development. An …

Complex 3D microfluidic architectures formed by mechanically guided compressive buckling

H Luan, Q Zhang, TL Liu, X Wang, S Zhao, H Wang… - Science …, 2021 - science.org
Microfluidic technologies have wide-ranging applications in chemical analysis systems, drug
delivery platforms, and artificial vascular networks. This latter area is particularly relevant to …

Biomimetic models of the glomerulus

MG Valverde, LS Mille, KP Figler, E Cervantes… - Nature Reviews …, 2022 - nature.com
The use of biomimetic models of the glomerulus has the potential to improve our
understanding of the pathogenesis of kidney diseases and to enable progress in …

Emerging roles of microfluidics in brain research: from cerebral fluids manipulation to brain-on-a-chip and neuroelectronic devices engineering

J Wan, S Zhou, HJ Mea, Y Guo, H Ku… - Chemical …, 2022 - ACS Publications
Remarkable progress made in the past few decades in brain research enables the
manipulation of neuronal activity in single neurons and neural circuits and thus allows the …

[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …

[HTML][HTML] Kidney-on-a-chip: mechanical stimulation and sensor integration

D Wang, M Gust, N Ferrell - Sensors, 2022 - mdpi.com
Bioengineered in vitro models of the kidney offer unprecedented opportunities to better
mimic the in vivo microenvironment. Kidney-on-a-chip technology reproduces 2D or 3D …

[HTML][HTML] Organs-on-Chips platforms are everywhere: A zoom on biomedical investigation

M Zommiti, N Connil, A Tahrioui, A Groboillot, C Barbey… - Bioengineering, 2022 - mdpi.com
Over the decades, conventional in vitro culture systems and animal models have been used
to study physiology, nutrient or drug metabolisms including mechanical and …

[HTML][HTML] Fluid flow to mimic organ function in 3D in vitro models

Y Juste-Lanas, S Hervas-Raluy, JM García-Aznar… - APL …, 2023 - pubs.aip.org
Many different strategies can be found in the literature to model organ physiology, tissue
functionality, and disease in vitro; however, most of these models lack the physiological fluid …