Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
Obesity II: establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
[HTML][HTML] Dysbiosis-induced secondary bile acid deficiency promotes intestinal inflammation
Secondary bile acids (SBAs) are derived from primary bile acids (PBAs) in a process reliant
on biosynthetic capabilities possessed by few microbes. To evaluate the role of BAs in …
on biosynthetic capabilities possessed by few microbes. To evaluate the role of BAs in …
[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders
JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …
disorders and metabolic syndrome have largely been attributed to genetic background and …
EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
Environmental obesogens: mechanisms and controversies
JJ Heindel, B Blumberg - Annual review of pharmacology and …, 2019 - annualreviews.org
Obesity is a worldwide pandemic in adults as well as children and adds greatly to health
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …
Metabolic syndrome and associated diseases: from the bench to the clinic
DL Mendrick, AM Diehl, LS Topor… - Toxicological …, 2018 - academic.oup.com
Abstract Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic, a
Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held on …
Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held on …
Oxidative stress in NAFLD: role of nutrients and food contaminants
C Rives, A Fougerat, S Ellero-Simatos, N Loiseau… - Biomolecules, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue
B Wang, EE Tsakiridis, S Zhang, A Llanos… - Nature …, 2021 - nature.com
Obesity results from a caloric imbalance between energy intake, absorption and
expenditure. In both rodents and humans, diet-induced thermogenesis contributes to energy …
expenditure. In both rodents and humans, diet-induced thermogenesis contributes to energy …
[HTML][HTML] Environmental obesogens and their impact on susceptibility to obesity: new mechanisms and chemicals
RJ Egusquiza, B Blumberg - Endocrinology, 2020 - academic.oup.com
The incidence of obesity has reached an all-time high, and this increase is observed
worldwide. There is a growing need to understand all the factors that contribute to obesity to …
worldwide. There is a growing need to understand all the factors that contribute to obesity to …