Research in autophagy continues to accelerate, 1 and as a result many new scientists are
entering the field. Accordingly, it is important to establish a standard set of criteria for …

Skeletal muscle fibrosis can be a devastating clinical problem that arises from many causes,
including primary skeletal muscle tissue diseases, as seen in the muscular dystrophies, or it …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Granulation tissue formation and contraction is an important step of second intention wound
healing. Granulation tissue develops from the connective tissue surrounding the damaged …

Recent evidence points to a strong relationship between increased mitochondrial
biogenesis and increased survival in eukaryotes. Branched-chain amino acids (BCAAs) …

The liver plays a central role in the control of glucose homeostasis and is subject to complex
regulation by substrates, insulin, and other hormones. To investigate the effect of the loss of …

The rapid growth of an aging population creates challenges regarding age-related diseases,
including AKI, for which both the prevalence and death rate increase with age. The …

The glucose analog streptozotocin (STZ) has long been used as a tool for creating
experimental diabetes because of its relatively specific β-cell cytotoxic effect, but the …

Background Renal renin-angiotensin system (RAS) activation is one of the important
pathogenic mechanisms in the development of diabetic nephropathy in type 2 diabetes. The …

Relationship between weight at birth and the number and size of renal glomeruli in humans:
A histomorphometric study. Background The number of nephrons in humans varies …