Host–transposon interactions: conflict, cooperation, and cooption
RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …
threaten genome integrity. As a result, several mechanisms appear to have emerged during …
Evolutionary entanglement of mobile genetic elements and host defence systems: guns for hire
EV Koonin, KS Makarova, YI Wolf… - Nature Reviews …, 2020 - nature.com
All cellular life forms are afflicted by diverse genetic parasites, including viruses and other
types of mobile genetic elements (MGEs), and have evolved multiple, diverse defence …
types of mobile genetic elements (MGEs), and have evolved multiple, diverse defence …
Programmed chromosome fragmentation in ciliated protozoa: multiple means to chromosome ends
M Bétermier, LA Klobutcher, E Orias - Microbiology and Molecular …, 2023 - Am Soc Microbiol
Ciliated protozoa undergo large-scale developmental rearrangement of their somatic
genomes when forming a new transcriptionally active macronucleus during conjugation …
genomes when forming a new transcriptionally active macronucleus during conjugation …
Programmed genome rearrangements in ciliates
I Rzeszutek, XX Maurer-Alcalá, M Nowacki - Cellular and Molecular Life …, 2020 - Springer
Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …
[HTML][HTML] Comprehensive chromosome end remodeling during programmed DNA elimination
J Wang, GMB Veronezi, Y Kang, M Zagoskin… - Current Biology, 2020 - cell.com
Germline and somatic genomes are in general the same in a multicellular organism.
However, programmed DNA elimination leads to a reduced somatic genome compared to …
However, programmed DNA elimination leads to a reduced somatic genome compared to …
Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements
C Miró-Pina, O Charmant, T Kawaguchi, D Holoch… - Developmental cell, 2022 - cell.com
Summary Polycomb repressive complex 2 (PRC2) maintains transcriptionally silent genes in
a repressed state via deposition of histone H3K27-trimethyl (me3) marks. PRC2 has also …
a repressed state via deposition of histone H3K27-trimethyl (me3) marks. PRC2 has also …
MITE infestation accommodated by genome editing in the germline genome of the ciliate Blepharisma
BKB Seah, M Singh, C Emmerich… - Proceedings of the …, 2023 - National Acad Sciences
During their development following sexual conjugation, ciliates excise numerous internal
eliminated sequences (IESs) from a copy of the germline genome to produce the functional …
eliminated sequences (IESs) from a copy of the germline genome to produce the functional …
Massive colonization of protein-coding exons by selfish genetic elements in Paramecium germline genomes
Ciliates are unicellular eukaryotes with both a germline genome and a somatic genome in
the same cytoplasm. The somatic macronucleus (MAC), responsible for gene expression, is …
the same cytoplasm. The somatic macronucleus (MAC), responsible for gene expression, is …
A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies
J Xu, X Zhao, F Mao, V Basrur… - Nucleic acids …, 2021 - academic.oup.com
Polycomb group (PcG) proteins are widely utilized for transcriptional repression in
eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E (z) …
eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E (z) …
Constitutive heterochromatin in eukaryotic genomes: A mine of transposable elements
RM Marsano, P Dimitri - Cells, 2022 - mdpi.com
Transposable elements (TEs) are abundant components of constitutive heterochromatin of
the most diverse evolutionarily distant organisms. TEs enrichment in constitutive …
the most diverse evolutionarily distant organisms. TEs enrichment in constitutive …