Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

All cellular life forms are afflicted by diverse genetic parasites, including viruses and other
types of mobile genetic elements (MGEs), and have evolved multiple, diverse defence …

Ciliated protozoa undergo large-scale developmental rearrangement of their somatic
genomes when forming a new transcriptionally active macronucleus during conjugation …

Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …

Germline and somatic genomes are in general the same in a multicellular organism.
However, programmed DNA elimination leads to a reduced somatic genome compared to …

Summary Polycomb repressive complex 2 (PRC2) maintains transcriptionally silent genes in
a repressed state via deposition of histone H3K27-trimethyl (me3) marks. PRC2 has also …

During their development following sexual conjugation, ciliates excise numerous internal
eliminated sequences (IESs) from a copy of the germline genome to produce the functional …

Ciliates are unicellular eukaryotes with both a germline genome and a somatic genome in
the same cytoplasm. The somatic macronucleus (MAC), responsible for gene expression, is …

Polycomb group (PcG) proteins are widely utilized for transcriptional repression in
eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E (z) …

Transposable elements (TEs) are abundant components of constitutive heterochromatin of
the most diverse evolutionarily distant organisms. TEs enrichment in constitutive …