RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
[HTML][HTML] Mitochondria on the move: Horizontal mitochondrial transfer in disease and health
Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …
types. This concept was challenged recently when cellular organelles including …
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
H Scheiblich, C Dansokho, D Mercan, SV Schmidt… - Cell, 2021 - cell.com
Microglia are the CNS resident immune cells that react to misfolded proteins through pattern
recognition receptor ligation and activation of inflammatory pathways. Here, we studied how …
recognition receptor ligation and activation of inflammatory pathways. Here, we studied how …
Tunneling nanotubes provide a route for SARS-CoV-2 spreading
A Pepe, S Pietropaoli, M Vos, G Barba-Spaeth… - Science …, 2022 - science.org
Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection represent a major issue in long coronavirus disease. How SARS-CoV-2 …
CoV-2) infection represent a major issue in long coronavirus disease. How SARS-CoV-2 …
Viral and host heterogeneity and their effects on the viral life cycle
JE Jones, V Le Sage, SS Lakdawala - Nature Reviews Microbiology, 2021 - nature.com
Traditionally, the viral replication cycle is envisioned as a single, well-defined loop with four
major steps: attachment and entry into a target cell, replication of the viral genome …
major steps: attachment and entry into a target cell, replication of the viral genome …
Mitochondria can cross cell boundaries: An overview of the biological relevance, pathophysiological implications and therapeutic perspectives of intercellular …
Mitochondria are complex intracellular organelles traditionally identified as the
powerhouses of eukaryotic cells due to their central role in bioenergetic metabolism. In …
powerhouses of eukaryotic cells due to their central role in bioenergetic metabolism. In …
The functions, methods, and mobility of mitochondrial transfer between cells
Y Qin, X Jiang, Q Yang, J Zhao, Q Zhou… - Frontiers in oncology, 2021 - frontiersin.org
Mitochondria are vital organelles in cells, regulating energy metabolism and apoptosis.
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …
Key gaps in the knowledge of the porcine respiratory reproductive syndrome virus (PRRSV)
S Montaner-Tarbes, HA Del Portillo… - Frontiers in veterinary …, 2019 - frontiersin.org
The porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
important swine diseases in the world. It is causing an enormous economic burden due to …
important swine diseases in the world. It is causing an enormous economic burden due to …
HSV-1 cytoplasmic envelopment and egress
I Ahmad, DW Wilson - International journal of molecular sciences, 2020 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …
[HTML][HTML] Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics
Z Payandeh, B Tangruksa, J Synnergren… - Molecular Aspects of …, 2024 - Elsevier
Modern methods of molecular diagnostics and therapy have revolutionized the field of
medicine in recent years by providing more precise and effective tools for detecting and …
medicine in recent years by providing more precise and effective tools for detecting and …