Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Hyaluronic acid and controlled release: A review

IS Bayer - Molecules, 2020 - mdpi.com
Hyaluronic acid (HA) also known as hyaluronan, is a natural polysaccharide—an anionic,
non-sulfated glycosaminoglycan—commonly found in our bodies. It occurs in the highest …

Hydrogels for therapeutic delivery: current developments and future directions

SJ Buwalda, T Vermonden, WE Hennink - Biomacromolecules, 2017 - ACS Publications
Hydrogels are attractive materials for the controlled release of therapeutics because of their
capacity to embed biologically active agents in their water-swollen network. Recent …

Hyaluronic acid for anticancer drug and nucleic acid delivery

F Dosio, S Arpicco, B Stella, E Fattal - Advanced drug delivery reviews, 2016 - Elsevier
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

Designing smart polymer conjugates for controlled release of payloads

F Seidi, R Jenjob, D Crespy - Chemical reviews, 2018 - ACS Publications
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …

Modified hyaluronic acid based materials for biomedical applications

S Tiwari, P Bahadur - International journal of biological macromolecules, 2019 - Elsevier
Hyaluronic acid (HA) is a high molecular weight, non-sulfated anionic polysaccharide from
glycosamine glycan family. It is a versatile biomaterial that binds to specific cell receptor …

Drug delivery systems based on CD44-targeted glycosaminoglycans for cancer therapy

M Li, J Sun, W Zhang, Y Zhao, S Zhang, S Zhang - Carbohydrate Polymers, 2021 - Elsevier
The polysaccharide-based biomaterials hyaluronic acid (HA) and chondroitin sulfate (CS)
have aroused great interest for use in drug delivery systems for tumor therapy, as they have …

Strategies for hyaluronic acid-based hydrogel design in drug delivery

S Trombino, C Servidio, F Curcio, R Cassano - Pharmaceutics, 2019 - mdpi.com
Hyaluronic acid (HA) is a natural, linear, endogenous polysaccharide that plays important
physiological and biological roles in the human body. Nowadays, among biopolymers, HA is …

Dual pH-responsive multifunctional nanoparticles for targeted treatment of breast cancer by combining immunotherapy and chemotherapy

Y Liu, L Qiao, S Zhang, G Wan, B Chen, P Zhou… - Acta Biomaterialia, 2018 - Elsevier
In the present study, a dual pH-responsive multifunctional nanoparticle system was
designed for combining immunotherapy and chemotherapy to treat breast cancer through …

Hyaluronic acid-based theranostic nanomedicines for targeted cancer therapy

SY Lee, MS Kang, WY Jeong, DW Han, KS Kim - Cancers, 2020 - mdpi.com
Hyaluronic acid (HA) is a natural mucopolysaccharide and has many useful advantages,
including biocompatibility, non-immunogenicity, chemical versatility, non-toxicity …