Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are
rare, life-threatening immunologic reactions. Prior studies using electronic health records …

Hospital-based registry data, including patients' information collected by academic societies
or government based research groups, were previously used for clinical research in Japan …

Clinicians, researchers, regulators, and other decision-makers increasingly rely on evidence
from real-world data (RWD), including data routinely accumulating in health and …

Importance Serious cutaneous adverse drug reactions (cADRs) are potentially life-
threatening drug hypersensitivity reactions involving the skin and internal organs. Antibiotics …

Background Evidence is lacking on the association between antibiotic use and risk of
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Asians. Objective …

Background Because severe cutaneous adverse reactions (SCARs), such as Stevens-
Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with …

Results We identified a total of 433 articles through our database search and included 140
articles in this systematic review (Fig. 1). Six main research topics were identified:(1) …

Background: Evidence for the risk and incidence of anticonvulsant-induced Stevens-
Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Japan is scarce. Methods …

Validation of an Algorithm to Identify Epidermal Necrolysis on a Medico-Administrative
Database Validation of an Algorithm to Identify Epidermal Necrolysis on a Medico-Administrative …

Methods: We conducted a population-based nested case-control study using multiple linked
healthcare datasets to examine the association between various oral antibiotics and serious …