[HTML][HTML] Olfactory neuropathology in Alzheimer's disease: a sign of ongoing neurodegeneration

G Son, A Jahanshahi, SJ Yoo, JT Boonstra… - BMB …, 2021 - ncbi.nlm.nih.gov
Olfactory neuropathology is a cause of olfactory loss in Alzheimer's disease (AD). Olfactory
dysfunction is also associated with memory and cognitive dysfunction and is an incidental …

Olfactory evaluation in Alzheimer's disease model mice

J Zhang, Z Zhao, S Sun, J Li, Y Wang, J Dong, S Yang… - Brain Sciences, 2022 - mdpi.com
Olfactory dysfunction is considered a pre-cognitive biomarker of Alzheimer's disease (AD).
Because the olfactory system is highly conserved across species, mouse models …

Distribution and inter-regional relationship of amyloid-beta plaque deposition in a 5xFAD mouse model of Alzheimer's disease

KC Tsui, J Roy, SC Chau, KH Wong, L Shi… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia. Although previous studies
have selectively investigated the localization of amyloid-beta (Aβ) deposition in certain brain …

Odor identification score as an alternative method for early identification of amyloidogenesis in Alzheimer's disease

Y Igeta, I Hemmi, K Yuyama, Y Ouchi - Scientific Reports, 2024 - nature.com
A simple screening test to identify the early stages of Alzheimer's disease (AD) is urgently
needed. We investigated whether odor identification impairment can be used to differentiate …

Spatiotemporal dynamics of the development of mouse olfactory system from prenatal to postnatal period

BR Kim, MS Rha, HJ Cho, JH Yoon… - Frontiers in …, 2023 - frontiersin.org
Introduction The olfactory epithelium (OE) and olfactory bulb (OB) are the major components
of the olfactory system and play critical roles in olfactory perception. However, the embryonic …

Medical aromatherapy in geriatric syndrome

T Ebihara, M Yamasaki, K Kozaki… - Geriatrics & …, 2021 - Wiley Online Library
Geriatric syndromes are symptoms and signs, such as falls, incontinence, delirium, pressure
ulcers, dysphagia and so on, that often threaten the independence of older adults, rather …

The Current Status and Challenges of Olfactory Dysfunction Study in Alzheimer's Disease

W Liao, Y Wang, J Li, D Huang, W Cheng… - Ageing Research …, 2024 - Elsevier
Olfactory functioning involves multiple cognitive processes and the coordinated actions of
various neural systems. Any disruption at any stage of this process may result in olfactory …

Severe histomorphological alterations in post‐mortem olfactory glomeruli in Alzheimer's disease

G Son, HWM Steinbusch, C López‐Iglesias… - Brain …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is the most prevalent form of dementia. Key AD symptoms include
memory and cognitive decline; however, comorbid symptoms such as depression and …

Post-COVID-19 Hyposmia Does Not Exhibit Main Neurodegeneration Markers in the Olfactory Pathway

T Schirinzi, D Maftei, R Maurizi, M Albanese… - Molecular …, 2024 - Springer
The biological substrate of persistent post-COVID-19 hyposmia is still unclear. However, as
many neurodegenerative diseases present with smell impairment at onset, it may …

[HTML][HTML] Verification of the association between cognitive decline and olfactory dysfunction using a DEmentia screening kit in subjects with Alzheimer's dementia, mild …

T Fukumoto, T Ezaki, K Urakami - Eneurologicalsci, 2022 - Elsevier
Background and purpose Olfactory dysfunction may be an early symptom of degenerative
neurological disorders such as mild cognitive impairment (MCI), which may progress to …