Objectives To assess cost-effectiveness of direct oral anticoagulants (DOACs) compared
with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) by pooling …

Background Atrial fibrillation (AF) remains the most common form of cardiac arrhythmia.
Management of AF aims to reduce the risk of stroke, heart failure and premature mortality via …

Aims The economic value of transcatheter aortic valve replacement (TAVR) in low surgical
risk patients with severe, symptomatic aortic stenosis is not known. Our objective was to …

Background and Purpose—The objective of the study is to compare the cost-effectiveness of
oral anticoagulants among atrial fibrillation patients at an increased stroke risk. Methods—A …

Objective Although transcatheter aortic valve implantation has been shown to be noninferior
to surgical aortic valve replacement in patients with severe aortic stenosis at intermediate …

Objectives The clinical and cost-saving benefits of transcatheter aortic valve implantation
(TAVI) over surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis …

Background A recent clinical trial showed that self-expandable transcatheter aortic valve
replacement (TAVR) was non-inferior to surgical aortic valve replacement (SAVR). However …

Background Transcatheter aortic valve implantation (TAVI) with the SAPIEN 3 device has
recently shown significant clinical benefits, compared to surgical aortic valve replacement …

Objectives Our objectives were to investigate the cost effectiveness of apixaban,
rivaroxaban, and dabigatran compared with coumarin derivatives for stroke prevention in …

Aims Atrial fibrillation (AF) is associated with numerous cardiovascular complications. We
sought to estimate the annual burden of cardiovascular complications in AF patients in …