The long non-coding RNA world in yeasts

A Yamashita, Y Shichino, M Yamamoto - Biochimica et Biophysica Acta …, 2016 - Elsevier
In recent years, it has become evident that eukaryotic genomes are pervasively transcribed
and produce numerous non-coding transcripts, including long non-coding RNAs (lncRNAs) …

Roles of lncRNA transcription as a novel regulator of chromosomal function

S Senmatsu, K Hirota - Genes & genetic systems, 2020 - jstage.jst.go.jp
In recent years, many transcriptome analyses have revealed that numerous noncoding
RNAs are transcribed in eukaryotic cells. Long noncoding RNAs (lncRNAs), which consist of …

Synthesis and Structure Elucidation of Glutamyl-Queuosine

A Pichler, M Hillmeier, M Heiss, E Peev… - Journal of the …, 2023 - ACS Publications
Queuosine is one of the most complex hypermodified RNA nucleosides found in the Wobble
position of tRNAs. In addition to Queuosine itself, several further modified derivatives are …

Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast

SR Atkinson, S Marguerat, DA Bitton… - Rna, 2018 - rnajournal.cshlp.org
Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable,
contribute a substantial and diverse portion to pervasive noncoding transcriptomes. Most …

Facultative heterochromatin formation in rDNA is essential for cell survival during nutritional starvation

H Hirai, N Takemata, M Tamura… - Nucleic Acids Research, 2022 - academic.oup.com
During the cellular adaptation to nutrient starvation, cells temporarily decelerate translation
processes including ribosomal biogenesis. However, the mechanisms repressing robust …

cAMP-Protein kinase A and stress-activated MAP kinase signaling mediate transcriptional control of autophagy in fission yeast during glucose limitation or starvation

AJ Pérez-Díaz, B Vázquez-Marín, J Vicente-Soler… - Autophagy, 2023 - Taylor & Francis
Macroautophagy/autophagy is an essential adaptive physiological response in eukaryotes
induced during nutrient starvation, including glucose, the primary immediate carbon and …

Comparative Research: Regulatory Mechanisms of Ribosomal Gene Transcription in Saccharomyces cerevisiae and Schizosaccharomyces pombe

H Hirai, K Ohta - Biomolecules, 2023 - mdpi.com
Restricting ribosome biosynthesis and assembly in response to nutrient starvation is a
universal phenomenon that enables cells to survive with limited intracellular resources …

Transposon Removal Reveals Their Adaptive Fitness Contribution

S Cranz-Mileva, E Reilly, N Chalhoub… - Genome biology and …, 2024 - academic.oup.com
Transposable elements are molecular parasites that persist in their host genome by
generating new copies to outpace natural selection. Transposable elements exert a large …

Effects of diet on aristolochic acid-DNA adduct formation: Implications for Balkan endemic nephropathy etiology

J Zhang, CK Chan, NM Pavlovic… - Chemical research in …, 2023 - ACS Publications
Prolonged exposure to aristolochic acids (AAs) through AA-containing herbal medicine or
AA-contaminated food is associated with the development of aristolochic acid nephropathy …

Functional profiling of long intergenic non-coding RNAs in fission yeast

M Rodriguez-Lopez, S Anver, C Cotobal, S Kamrad… - Elife, 2022 - elifesciences.org
Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that
do not overlap any coding genes. Some lincRNAs function in various aspects of gene …