Exposure to early life stress (ELS) causes abnormal hippocampal development and
functional deficits in rodents and humans, but no meta-analysis has been used yet to …

The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural
stem cells. Newborn neurons integrate into existing neuronal networks, where they play a …

Early life stress (ELS) causes long-lasting changes in brain plasticity induced by the
exposure to stress factors acting prenatally or in the early postnatal ontogenesis due to …

Background Early-life stress (ES) is an emerging risk factor for later life development of
Alzheimer's disease (AD). We have previously shown that ES modulates amyloid-beta …

Exposure to stressors in early postnatal life induces long-lasting modifications in brain
function. This plasticity, an essential characteristic of the brain that enables adaptation to the …

Early adversity is an important risk factor that influences brain aging. Diverse animal models
of early adversity, including gestational stress and postnatal paradigms disrupting dam-pup …

Neuroinflammation plays a crucial role in the pathogenesis and progression of Alzheimer's
disease (AD). The Sterile Alpha and Toll Interleukin Receptor Motif-containing protein 1 …

Soluble amyloid precursor protein-alpha (sAPPα) is a regulator of neuronal and memory
mechanisms, while also having neurogenic and neuroprotective effects in the brain. As adult …

Early-life stress (ES) increases the risk for psychopathology and cognitive decline later in
life. Because the neurobiological substrates affected by ES (ie, cognition, neuroplasticity …

INTRODUCTION Early‐life stress (ES) increases the risk for Alzheimer's disease (AD). We
and others have shown that ES aggravates amyloid‐beta (Aβ) pathology and promotes …