[HTML][HTML] Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes

K Kistamás, A Müller, S Muenthaisong… - Journal of Molecular …, 2023 - Elsevier
Cardiovascular diseases are the leading cause of death worldwide. Several strategies–
small molecules, gene therapy, surgeries, cardiac rehabilitation–have been developed to …

Molecular insights of exercise therapy in disease prevention and treatment

D Walzik, TY Wences Chirino, P Zimmer… - Signal Transduction and …, 2024 - nature.com
Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the
prevention and treatment of various diseases, the underlying biological mechanisms have …

A comprehensive protocol combining in vivo and ex vivo electrophysiological experiments in an arrhythmogenic animal model

M Nyman, TO Stølen, AB Johnsen… - American Journal …, 2024 - journals.physiology.org
Ventricular arrhythmias contribute significantly to cardiovascular mortality, with coronary
artery disease as the predominant underlying cause. Understanding the mechanisms of …

The effects of MicroRNAs in the development of heart failure

YT Guo, YC Xiao, Y Xu, JF Fan, LY Niu, X Tan… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review Heart failure is a severe clinical syndrome with complex and
unclarified mechanisms, and it poses a serious threat to human health. MicroRNA, a non …

[HTML][HTML] Identification of candidate genes and pathways in limonin-mediated cardiac repair after myocardial infarction

W Xiong, S Feng, H Wang, S Qing, Y Yang… - Biomedicine & …, 2021 - Elsevier
Background Myocardial infarction (MI) resulting from acute coronary ischemia may cause
significant morbidity and mortality, and microRNAs play a vital role in this pathophysiology …

Exercise heat acclimation causes human responses and safety performance improvements

S Zhang, N Zhu - Journal of Thermal Biology, 2021 - Elsevier
Heat acclimation (HA) is a widely recognized physiological phenomenon of human body in
hot environments. HA has many benefits, such aspreventing hyperthermia responses, and is …

[Retracted] miR‐214‐3p Protects and Restores the Myocardial Tissue of Rat Myocardial Infarction Model by Targeting PTEN

Y Cheng, Q He, T Jin, N Li - Evidence‐Based Complementary …, 2022 - Wiley Online Library
Myocardial infarction (MI), which results in myocardial cell dysfunction and irreversible loss,
is one of the most serious health threats today. This study was started with rats, by which the …

Exercise mediates myocardial infarction via non-coding RNAs

C Han, C Zhai, A Li, Y Ma… - Frontiers in Cardiovascular …, 2024 - frontiersin.org
Myocardial infarction (MI), a widespread cardiovascular issue, mainly occurs due to blood
clot formation in the coronary arteries, which reduces blood flow to the heart muscle and …

[HTML][HTML] Exercise Training-Induced MicroRNA Alterations with Protective Effects in Cardiovascular Diseases

J Gao, J Song, Y Yan, P Gokulnath… - Reviews in …, 2023 - imrpress.com
Exercise training (ET) is an important non-drug adjuvant therapy against many human
diseases, including cardiovascular diseases. The appropriate ET intensity induces …

The Degree of Cardiac Remodelling before Overload Relief Triggers Different Transcriptome and miRome Signatures during Reverse Remodelling (RR)—Molecular …

PG Rodrigues, D Miranda-Silva, X Li… - International journal of …, 2020 - mdpi.com
This study aims to provide new insights into transcriptome and miRome modifications
occurring in cardiac reverse remodelling (RR) upon left ventricle pressure-overload relief in …