A systematic review of miRNAs as biomarkers for chemotherapy-induced cardiotoxicity in breast cancer patients reveals potentially clinically informative panels as well …

C Brown, M Mantzaris, E Nicolaou, G Karanasiou… - Cardio-Oncology, 2022 - Springer
Breast cancer patients are at a particularly high risk of cardiotoxicity from chemotherapy
having a detrimental effect on quality-of-life parameters and increasing the risk of mortality …

MiR-29a-3p: A potential biomarker and therapeutic target in colorectal cancer

WY Mo, SQ Cao - Clinical and Translational Oncology, 2023 - Springer
Cancer is frequently caused by microRNAs, which control post-transcriptional levels of gene
expression by binding to target mRNAs. MiR-29a-3p has recently been shown to play a …

Cardiovascular disease-associated microRNAs as novel biomarkers of first-trimester screening for gestational diabetes mellitus in the absence of other pregnancy …

I Hromadnikova, K Kotlabova, L Krofta - International Journal of Molecular …, 2022 - mdpi.com
We assessed the diagnostic potential of cardiovascular disease-associated microRNAs for
the early prediction of gestational diabetes mellitus (GDM) in singleton pregnancies of …

miR-29a-3p/THBS2 axis regulates PAH-induced cardiac fibrosis

CH Hsu, IF Liu, HF Kuo, CY Li, WS Lian… - International journal of …, 2021 - mdpi.com
Pulmonary artery hypertension (PAH) pathology involves extracellular matrix (ECM)
remodeling in cardiac tissues, thus promoting cardiac fibrosis progression. miR-29a-3p …

Diabetes mellitus and cardiovascular risk assessment in mothers with a history of gestational diabetes mellitus based on postpartal expression profile of micrornas …

I Hromadnikova, K Kotlabova, L Dvorakova… - International journal of …, 2020 - mdpi.com
Mothers with a history of gestational diabetes mellitus (GDM) have an increased risk of
developing diabetes in the future and a lifelong cardiovascular risk. Postpartal expression …

Epigenetic regulation of endothelial dysfunction and inflammation in pulmonary arterial hypertension

J Hudson, L Farkas - International journal of molecular sciences, 2021 - mdpi.com
Once perceived as a disorder treated by vasodilation, pulmonary artery hypertension (PAH)
has emerged as a pulmonary vascular disease with severe endothelial cell dysfunction. In …

Substantially altered expression profile of diabetes/cardiovascular/cerebrovascular disease associated microRNAs in children descending from pregnancy …

I Hromadnikova, K Kotlabova, L Dvorakova, L Krofta… - Cells, 2020 - mdpi.com
Gestational diabetes mellitus (GDM), one of the major pregnancy-related complications,
characterized as a transitory form of diabetes induced by insulin resistance accompanied by …

[HTML][HTML] Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid …

V Agrawal, T Lahm, G Hansmann… - … Diagnosis and Therapy, 2020 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is a rare, life-threatening condition characterized by
dysregulated metabolism, pulmonary vascular remodeling, and loss of pulmonary vascular …

Right Ventricle and Epigenetics: A Systematic Review

V Toro, N Jutras-Beaudoin, O Boucherat, S Bonnet… - Cells, 2023 - mdpi.com
There is an increasing recognition of the crucial role of the right ventricle (RV) in determining
the functional status and prognosis in multiple conditions. In the past decade, the epigenetic …

Molecular characterization and elucidation of pathways to identify novel therapeutic targets in pulmonary arterial hypertension

X Yao, T Jing, T Wang, C Gu, X Chen, F Chen… - Frontiers in …, 2021 - frontiersin.org
Background: Pulmonary arterial hypertension (PAH) is a life-threatening chronic
cardiopulmonary disease. However, there are limited studies reflecting the available …