Inflammation in first‐episode psychosis: the contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta‐analysis

C Dunleavy, RJ Elsworthy… - Acta Psychiatrica …, 2022 - Wiley Online Library
Objective To provide a comprehensive analysis of cytokine perturbations in antipsychotic‐
naïve first‐episode psychosis (FEP) populations and assess the relationship between …

The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia

KS Na, HY Jung, YK Kim - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Schizophrenia is a serious mental illness with chronic symptoms and significant impairment
in psychosocial functioning. Although novel antipsychotics have been developed, the …

Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects

BJ Miller, P Buckley, W Seabolt, A Mellor… - Biological …, 2011 - Elsevier
BACKGROUND: Schizophrenia is associated with immune system dysfunction, including
aberrant cytokine levels. We performed a meta-analysis of these associations, considering …

Inflammation and schizophrenia

B Kirkpatrick, BJ Miller - Schizophrenia bulletin, 2013 - academic.oup.com
Inflammation is one of the body's first lines of defense in response to injury or infection, and
increased inflammation is found in many diseases. Acute inflammation is a nonspecific …

Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: a systematic review of biomarker studies

MJ Stuart, BT Baune - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
The search for immune biomarkers in psychiatric disorders has primarily focused on pro-
inflammatory cytokines. Other immune proteins including chemokines have been relatively …

Inflammation in schizophrenia: a question of balance

JC Leza, B García-Bueno, M Bioque, C Arango… - Neuroscience & …, 2015 - Elsevier
In the past decade, there has been renewed interest in immune/inflammatory changes and
their associated oxidative/nitrosative consequences as key pathophysiological mechanisms …

Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment

L de Witte, J Tomasik, E Schwarz, PC Guest… - Schizophrenia …, 2014 - Elsevier
Schizophrenia has been associated with central nervous system and peripheral immune
system imbalances. However, most studies have not yielded conclusive results due to …

Cytokines in cerebrospinal fluid of patients with schizophrenia spectrum disorders: New data and an updated meta-analysis

JA Gallego, EA Blanco, S Husain-Krautter… - Schizophrenia …, 2018 - Elsevier
Few studies have been conducted examining cytokines in cerebrospinal fluid of patients
compared to healthy volunteers. The goals of this study were: 1) to report original data …

[HTML][HTML] Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia …

S Hope, T Ueland, NE Steen, I Dieset, S Lorentzen… - Schizophrenia …, 2013 - Elsevier
BACKGROUND: Previous studies suggest elevated inflammation in schizophrenia and
bipolar disorder, with increased activity of the Interleukin 1 (IL-1), interleukin 6 (IL-6), tumor …

Kinetics of cytokine levels during antipsychotic treatment in schizophrenia: a meta-analysis

B Romeo, M Brunet-Lecomte, C Martelli… - International Journal …, 2018 - academic.oup.com
Background Immune system dysfunction is a hypothesis in the psychopathology of
schizophrenia, but the impact of antipsychotic treatment within this system is not clear. The …