Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

Brain aging is associated with diminished circadian clock output and decreased expression
of the core clock proteins, which regulate many aspects of cellular biochemistry and …

Ageing leads to a functional deterioration of many brain systems, including the circadian
clock—an internal time-keeping system that generates∼ 24-hour rhythms in physiology and …

The plus-maze, the light–dark box and the open-field are the main current tests of
unconditioned anxiety for mice and rats. Despite their disappointing achievements, they …

The circadian nature of mood and its dysfunction in affective disorders is well recognized,
but the underlying molecular mechanisms are still unclear. Here, we show that the circadian …

Daily rhythms in behavior and physiology are programmed by a hierarchical collection of
biological clocks located throughout the brain and body, known as the circadian system …

During wakefulness, extracellular levels of metabolites in the brain increase. These include
amyloid beta (Aβ), which contributes to the pathogenesis of Alzheimer's disease (AD) …

Circadian disruption has become more prevalent in society due to the increase in shift work,
sleep disruption, blue light exposure, and travel via different time zones. The circadian …

Modulation of basic biochemical and physiological processes by the circadian timing system
is now recognized as a fundamental feature of all mammalian organ systems. Within the …