Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and
can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) …

Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

Background Blood purification through the removal of plasma solutes by adsorption to
beads of charcoal or resins contained in a cartridge (hemoperfusion) has a long and …

Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Sepsis is a common condition that is associated with unacceptably high mortality and, for
many of those who survive, long-term morbidity. Increased awareness of the condition …

Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …

Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …

Importance Polymyxin B hemoperfusion reduces blood endotoxin levels in sepsis.
Endotoxin activity can be measured in blood with a rapid assay. Treating patients with septic …