Macrophages in heterotopic ossification: from mechanisms to therapy

Y Huang, X Wang, D Zhou, W Zhou, F Dai… - NPJ Regenerative …, 2021 - nature.com
Heterotopic ossification (HO) is the formation of extraskeletal bone in non-osseous tissues. It
is caused by an injury that stimulates abnormal tissue healing and regeneration, and …

The mechanisms of nanoparticle delivery to solid tumours

LNM Nguyen, W Ngo, ZP Lin, S Sindhwani… - Nature Reviews …, 2024 - nature.com
Nanoparticles for the detection and treatment of cancer have suffered from limited clinical
translation. A key problem has been the lack of understanding of the mechanisms of …

Targeting of hepatic macrophages by therapeutic nanoparticles

CI Colino, JM Lanao, C Gutierrez-Millan - Frontiers in immunology, 2020 - frontiersin.org
Hepatic macrophage populations include different types of cells with plastic properties that
can differentiate into diverse phenotypes to modulate their properties in response to different …

Intrinsic stimuli‐responsive nanocarriers for smart drug delivery of antibacterial agents—An in‐depth review of the last two decades

N Devnarain, N Osman, VO Fasiku… - Wiley …, 2021 - Wiley Online Library
Antibiotic resistance due to suboptimal targeting and inconsistent antibiotic release at
bacterial infection sites has driven the formulation of stimuli‐responsive nanocarriers for …

“Dual sensitive supramolecular curcumin nanoparticles” in “advanced yeast particles” mediate macrophage reprogramming, ROS scavenging and inflammation …

X Han, R Luo, S Qi, Y Wang, L Dai, W Nie, M Lin… - Journal of …, 2023 - Springer
Ulcerative colitis (UC) faces some barriers in oral therapy, such as how to safely deliver
drugs to the colon and accumulate in the colon lesions. Hence, we report an advanced yeast …

Functional nanozyme mediated multi-readout and label-free lateral flow immunoassay for rapid detection of Escherichia coli O157: H7

Z Wang, X Yao, Y Zhang, R Wang, Y Ji, J Sun, D Zhang… - Food chemistry, 2020 - Elsevier
To overcome the drawbacks of antibody labeling dependence and single-readout system in
the conventional lateral flow immunoassays (LFIAs) as well as the non-targeted combination …

[HTML][HTML] Polymer-and lipid-based gene delivery technology for CAR T cell therapy

IS Pinto, RA Cordeiro, H Faneca - Journal of Controlled Release, 2023 - Elsevier
Chimeric antigen receptor T cell (CAR T cell) therapy is a revolutionary approach approved
by the FDA and EMA to treat B cell malignancies and multiple myeloma. The production of …

[HTML][HTML] The increased ratio of Mg2+/Ca2+ from degrading magnesium alloys directs macrophage fate for functionalized growth of endothelial cells

Y Hou, F Witte, J Li, S Guan - Smart Materials in Medicine, 2022 - Elsevier
Biomedical magnesium (Mg) alloys have been widely studied as important structural
materials and biodegradable materials in cardiovascular stents system. However …

Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis

H Yang, J Li, SK Patel, KE Palmer, B Devlin, LC Rohan - Pharmaceutics, 2019 - mdpi.com
Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine
antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention …

Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy

S Rojekar, AD Gholap, N Togre, P Bhoj… - Journal of Controlled …, 2024 - Elsevier
In the pursuit of achieving better therapeutic outcomes in the treatment of HIV, innovative
drug delivery strategies have been extensively explored. Mannose receptors, which are …