Obesity and bone: a complex relationship
G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …
conclude from this review is that the increase in body weight causes an increase in BMD …
Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity
KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
[HTML][HTML] M2 macrophage-derived exosomes promote diabetic fracture healing by acting as an immunomodulator
Y Wang, Q Lin, H Zhang, S Wang, J Cui, Y Hu, J Liu… - Bioactive materials, 2023 - Elsevier
Diabetes mellitus is a chronically inflamed disease that predisposes to delayed fracture
healing. Macrophages play a key role in the process of fracture healing by undergoing …
healing. Macrophages play a key role in the process of fracture healing by undergoing …
Obesity and bone health: a complex link
J Hou, C He, W He, M Yang, X Luo, C Li - Frontiers in cell and …, 2020 - frontiersin.org
So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …
the results are inconsistent. Obesity is thought to affect bone health through a variety of …
Osteometabolism: metabolic alterations in bone pathologies
Renewing interest in the study of intermediate metabolism and cellular bioenergetics is
brought on by the global increase in the prevalence of metabolic illnesses. Understanding of …
brought on by the global increase in the prevalence of metabolic illnesses. Understanding of …
The impact of type 2 diabetes on bone fracture healing
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease known by the presence of
elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a …
elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a …
Bone marrow adipose tissue: to be or not to be a typical adipose tissue?
P Hardouin, T Rharass, S Lucas - Frontiers in endocrinology, 2016 - frontiersin.org
Bone marrow adipose tissue (BMAT) emerges as a distinct fat depot whose importance has
been proved in the bone–fat interaction. Indeed, it is well recognized that adipokines and …
been proved in the bone–fat interaction. Indeed, it is well recognized that adipokines and …
Dual effects of lipid metabolism on osteoblast function
NS Alekos, MC Moorer, RC Riddle - Frontiers in Endocrinology, 2020 - frontiersin.org
The skeleton is a dynamic and metabolically active organ with the capacity to influence
whole body metabolism. This newly recognized function has propagated interest in the …
whole body metabolism. This newly recognized function has propagated interest in the …
Cellular and molecular mechanisms associating obesity to bone loss
YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …
eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice
J Li, X Li, D Liu, K Hamamura, Q Wan, S Na… - Cell Death & …, 2019 - nature.com
Bone loss in postmenopausal osteoporosis is induced chiefly by an imbalance of bone-
forming osteoblasts and bone-resorbing osteoclasts. Salubrinal is a synthetic compound that …
forming osteoblasts and bone-resorbing osteoclasts. Salubrinal is a synthetic compound that …