Background Clostridium difficile is a leading cause of morbidity and mortality in several
countries. However, there are limited evidence characterizing its role as a global public …

Clostridium difficile is the main causative agent of antibiotic-associated and health care-
associated infective diarrhea. Recently, there has been growing interest in alternative …

The gold standard for clinical diagnosis of bacterial lower respiratory infections (LRIs) is
culture, which has poor sensitivity and is too slow to guide early, targeted antimicrobial …

Evidence from cross-sectional human studies, and preliminary microbial-based intervention
studies, have implicated the microbiota-gut-brain axis in the neurobiology of autism …

Short chain fatty acids (SCFAs) being produced during fermentation of non-digestible
polysaccharides are regulatory compounds with the potential to influence inflammatory, as …

The establishment of the infant gut microbiota is a highly dynamic process dependent on
extrinsic and intrinsic factors. We characterized the faecal microbiota of 4 breastfed infants …

Clostridioides difficile is an anaerobic Gram-positive and spore-forming bacterium. The
majority of C. difficile strains produce two toxins, A and B, associated with the development …

Clostridium difficile is a significant pathogen with over 300 000 cases reported in North
America annually. Previously, it was thought that C. difficile was primarily a clinically …

Antibiotic-associated diarrhea (AAD) is defined as diarrhea associated with antibiotic
exposure, either while on antibiotics, or for up to 8 weeks after antibiotic discontinuation. 1, 2 …

There has been an increase in the prevalence of Clostridioides difficile (C. diff) causing
significant economic impact on the health care system. Although toxigenic C. diff carriage is …