Sjögren's syndrome is a chronic autoimmune disease characterized by ocular and oral
dryness resulting from lacrimal and salivary gland dysfunction. Besides, a variety of systemic …

The B cell activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a B cell survival
factor which supports autoreactive B cells and prevents their deletion. BAFF expression is …

Objectives To update the EULAR recommendations for the management of systemic lupus
erythematosus (SLE) based on emerging new evidence. Methods An international Task …

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease
affecting both adults and children. Belimumab is the only biologic approved for SLE, and the …

Objective To develop evidence-based recommendations for the non-pharmacological
management of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc). Methods …

Artificial intelligence (AI)-based predictive models are being used to foster a precision
medicine approach to treat complex chronic diseases such as autoimmune and …

Disease modification has become a well-established concept in several therapeutic areas;
however, no widely accepted definition of disease modification exists for SLE. We reviewed …

Systemic lupus erythematosus (SLE) is an immune-mediated multi-systemic disease
characterized by a wide variability of clinical manifestations and a course frequently subject …

Background Belimumab was recently approved for treatment of lupus glomerulonephritis
(LN). Aim To evaluate renal response and its predictors in LN patients receiving belimumab …

B cell hyperactivity is a hallmark of the complex autoimmune disease systemic lupus
erythematosus (SLE), which has justified drug development focusing on B cell altering …